Histologic Diagnosis of Inflammatory Skin Diseases

Images

…bscuration of the junction by inflammatory cells, and hints of subepidermal fibrin = Linear IgA dermatosis Findings just like these may be seen in dermatitis herpetiformis. 10.19.2A: Vesicular dermatitis, subepidermal, neutrophils predominant +…

Histologic Diagnosis of Inflammatory Skin Diseases

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…ominant = Interstitial granulomatous dermatitis with arthritis Some histiocytes have abnormal nuclei and some of them are in mitosis. Histiocytes tend to be arrayed in a palisade around tiny foci of degenerated collagen, as well as being arranged in…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

…a method for calculation based on logical thought and orderly sequence, one that can be utilized for diagnosis of diseases of all kinds, including inflammatory ones of the skin. Once a disorder of the skin and/or subcutaneous fat has been determined…

Histologic Diagnosis of Inflammatory Skin Diseases

Thrombophlebitis

Thrombophlebitis Presentation stereotypical Age and sex Women most commonly Distribution of lesions Localized to the lower extremities usually Arrangement of lesions Linear often, i.e., along the course of a vein Individual lesions Cord sometimes in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pernio, Perniosis, Lupus Pernio, Chilblain, and Chilblain Lupus?

…“Several conditions have been described as predisposing subjects to pernio, including the presence of cryoproteins, excessive cold exposure, and anorexia nervosa among children and systemic lupus erythematosus and antiphospholipid antibodies a…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

s disease are reminiscent of those in pyoderma gangrenosum and Sweet’s syndrome. In this section, the dense infiltrates of neutrophils do not seem to be secondary to a suppurative infundibulitis. In some lesions of Beh├žet’s disease, howev…

Histologic Diagnosis of Inflammatory Skin Diseases

Erysipelas

Erysipelas Synonyms St. Anthony’s fire Ignis sacer Erysipele Erysipela Presentation stereotypical Age and sex Any age and either sex, but with a predilection for older persons with diabetes, peripheral vascular disease, and abuse of alcohol…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema elevatum diutinum

Erythema elevatum diutinum Presentation stereotypical Age and sex Any age, but usually young adults, women especially Distribution of lesions Symmetrical over joints especially, particularly the dorsa of the hands and the elbows and knees Shape of l…

Histologic Diagnosis of Inflammatory Skin Diseases

Sarcoidosis

Sarcoidosis Synonyms Boeck’s disease Boeck sarcoid Benign lymphogranulomatosis Presentation stereotypical Age and sex Young adults of both sexes Distribution of lesions Face and extremities especially Arrangement of lesions Scattered Configu…