Differential Diagnosis in Dermatopathology

Discussions

Spongiotic dermatitis with discrete collections of cells in the epidermis and mycosis fungoides with discrete collections of cells in the epidermis (Pautrier’s “microabscesses”) share some findings histopathologic, including the pr…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphatics

…s enables clearance from the dermis of fluids, macromolecules, cells, and foreign material. The twin roles of the lymphatic network as a conduit for Langerhanscells and as an exit for macromolecules such as lipids, proteins, and immune comple…

Histologic Diagnosis of Inflammatory Skin Diseases

Gianotti-Crosti disease

…one another, if only partially, thereby causing those spinous cells to assume a stellate shape, and the “pale cells” devoid of intercellular bridges and stellate shape, they being Langerhanscells. Spongiotic simulation of Pautrie…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ologic, namely, erythema annulare centrifugum). Collections of cells in the epidermis that vaguely resemble those in mycosis fungoides named for Pautrier actually consist here mostly of keratocytes and Langerhans”, they being joined by a few ly…

Dermatology Practical & Conceptual

European dermatology: great past-no future?

…I was a resident, we did not really feel that the function of Langerhans cells would ever be unraveled, that melanoma could ever be defeated, and that the cause of genodermatoses would ever be pinpointed. Today, we are very close to all these answer…