Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus Versus Systemic Lupus Erythematosus?* I

…develop systemic disease…” McKee PH, Calonje E, Granter SR. Pathology of the Skin. 3rd ed. 2005:775. Once upon a time, dermatologists and pathologists could never conceive of psoriasis, dermatitis herpetiformis, and granuloma faciale/erythema…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Focus of Infection?

…, and the remaining 45% remained etiologically undiagnosed. He stressed that the infection need not be extensive and cited a case of urticaria caused by a granuloma at the base of a tooth root. The search for the ‘hidden focus of infection&#821…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…replete with fibrin, is typical of rheumatoid nodule. Findings similar to these are met with in some patients with rheumatic fever. 10.93.2A: Panniculitis, lobular, granulomatous + 10.93.2B: Epithelioid histiocytes aligned in a palisade aro…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…atitis + 10.52.2B: Histiocytes, many with abnormal nuclei, scattered among collagen bundles in conjunction with lymphocytes, plasma cells, and neutrophils = Interstitial granulomatous dermatitis with arthritis The infiltrate in the section pictur…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Normal, Typical, Ordinary, Banal, and Common Nevus?

…n not contrasting (common versus uncommon) but, paradoxically, so-called dysplastic (Clark’s) nevus is more common by far than any so-called common nevus. Other melanocytic nevi, such as Unna’s, Mieschers, and Spitz’s, also a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Benign and Malignant Cells?

st is the recognition that cells of a benign neoplasm may have startlingly large and pleomorphic nuclei, e.g., those of some Spitz nevi and of ancient Mieschers nevi, and in reverse, cells of some malignant neoplasms may display remarkably sma…