Dermatology Practical & Conceptual

Yellow color upon dermatoscopy does not exclude melanoma!

In this issue, Rosendahl and colleagues report a case of non-choroidal melanoma that shows a strikingly unusual dermatoscopic aspect, namely, structureless yellow color. The authors correlate the yellow color to the presence of lipofuscin using tiss…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

Junctional epidermolysis bullosa Presentation stereotypical Age and sex Onset at birth in both sexes Distribution of lesions Widespread Individual lesions Vesicles, bullae, and vegetating crusts atop ulcers Course Blisters heal with slight scarring….

Differential Diagnosis in Dermatopathology

Discussions

…remarkable feature of nuclei of fibrocytes in some collagenous nevi is their startling atypia. Connective tissue nevi of the skin, in general, are hamartomas that consist of alterations of one or more components of the extracellular matrix: collagen,…

Differential Diagnosis in Dermatopathology

Discussions

Epidermolytic hyperkeratosis and a plane wart share several findings histopathologic, among them being a papillated and thickened epidermis, hypergranulosis, and cells with pale cytoplasm within the epidermis. The terms “epidermolytic hyperker…

Differential Diagnosis in Dermatopathology

Epidermolytic hyperkeratosis vs. Plane wart

An inflammatory process in which lesions present themselves clinically as red macules and subtle scaly papules. They soon become so confluent that there is widespread redness and scaling punctuated by islands of skin that ostensibly are spared and b…