Differential Diagnosis in Dermatopathology

Differential Diagnosis

…ymphocytes usually sparse 6. Infiltrate of lymphocytes often peri-infundibular and perifollicular 6. Infiltrate of lymphocytes has no predilection for infundibulofollicular units 7. Infiltrate may be lichenoid 7. Infiltrate not lichenoid 8. Sid…

Differential Diagnosis in Dermatopathology

Discussions

Lichen simplex chronicus and hypertrophic lichen planus are both responses to persistent, vigorous rubbing. In fact, lichen simplex chronicus results entirely from rubbing what at first was normal skin, in contrast to hypertrophic lichen planus whic…

Differential Diagnosis in Dermatopathology

Discussions

Atrophic lichen planus and atrophic discoid lupus erythematosus pose problems in differential diagnosis histopathologic because they have several findings in common, among them compact orthokeratosis, focal hypergranulosis, epidermis thinned and ass…

Differential Diagnosis in Dermatopathology

Discussions

In an urticarial reaction to an assault by an arthropod and in lesions of true urtica, the infiltrate of inflammatory cells is mixed, contains at least lymphocytes and usually eosinophils, and is accompanied by extravasated erythrocytes and edema of…

Dermatology Practical & Conceptual

Papillary adenocarcinoma in situ of the skin: report of four cases

Abstract Although rare isolated cases of adenocarcinoma in situ of skin have been reported in the literature, adenocarcinoma in situ of skin as a concept and as a diagnostic category has not been established in the field of dermatopathology. In this…

Differential Diagnosis in Dermatopathology

Discoid lupus erythematosus vs. Dermatomyositis

An inflammatory process that often begins as a suppurative folliculitis manifested clinically as pustules. It rapidly extends to become ulcers marked at their periphery by boggy tissue. The skin disease is associated commonly with inflammatory bowel…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…e dermis as a rule 4. Moderately dense superficial and deep, perivascular and interstitial, mixed-cell infiltrate; sometimes superficial only 4. Sparse superficial and deep perivascular and predominantly interstitial mixed-cell infiltrate; sometime…

Differential Diagnosis in Dermatopathology

Discussions

…s secondary syphilis. Lichen striatus often is associated with peri-infundibilitis and perifolliculitis, eccrine adenitis, and edema of the papillary dermis, three findings that are not present in lichen nitidus. The combination of spongiosis and lic…

Histologic Diagnosis of Inflammatory Skin Diseases

Seborrheic dermatitis

Seborrheic dermatitis Synonyms Seborrhoeic dermatitis Seborrheic eczema Unna disease Presentation stereotypical Age and sex Young adults especially and males in particular Distribution of lesions Face, scalp, retroauricular area, and V region of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiosis lipoidica

…yellow. Findings histopathologic Early Superficial and deep perivascular infiltrate of lymphocytes and neutrophils, and interstitial infiltrate of neutrophils Neutrophils present in septa of the subcutaneous fat and at the periphery of fat lobules…