Differential Diagnosis in Dermatopathology

Discussions

Allergic (leukocytoclastic) vasculitis and septic vasculitis have several attributes histopathologic in common, namely, signs of vasculitis, neutrophils in the dermal infiltrate, extravasated erythrocytes, and tendency to necrosis of the surface epi…

Differential Diagnosis in Dermatopathology

Allergic (leukocytoclastic) vasculitis vs. Septic vasculitis

An inflammatory process, i.e., a panniculitis, marked by tender erythematous plaques, nodules, or tumors (or combinations thereof) that usually affect the anterior aspect of the legs and, less often, the arms, and induced by processes, in an organ o…

Dermatology Practical & Conceptual

Review of Practical Dermatopathology by Ronald P. Rapini

…8220;A Transition” Dear Readers of the Book Reviews, It is now some 10 years since I became the book review editor of Dermatopathology: Practical & Conceptual. When that journal closed and became Dermatology Practical & Conceptual, I stayed o…

Histologic Diagnosis of Inflammatory Skin Diseases

Destombes-Rosai-Dorfman disease

Destombes-Rosai-Dorfman disease Synonyms Rosai-Dorfman disease Rosai-Dorfman histiocytosis Sinus histiocytosis with massive lymphadenopathy Presentation stereotypical Age and sex Usually in males under 25 years of age Distribution of lesions Localiz…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum

Erythema nodosum Synonyms Erythema contusiforme Erythema contusiformis Dermatitis contusiformis Erythema nouesux Presentation stereotypical Age and sex Young adults, especially women Distribution of lesions Bilateral and symmetrical over the pretibi…

Histologic Diagnosis of Inflammatory Skin Diseases

Blister secondary to hypoxemia and local pressure

Blister secondary to hypoxemia and local pressure Presentation stereotypical Age and sex Any age and either sex Distribution of lesions Sites of pressure Configuration of lesions Linear often, especially over wings of scapulae Individual lesions Ery…

Histologic Diagnosis of Inflammatory Skin Diseases

Borreliosis (erythema migrans)

Borreliosis (erythema migrans) Presentation stereotypical Age and sex Any age and either sex Distribution of lesions Nearly anywhere, but mostly the lower extremities; involvement of face and scalp is more common in children Configuration of lesions

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular vasculitis

Nodular vasculitis Presentation stereotypical Age and sex Middle-aged, thick-legged women Distribution of lesions Usually bilateral and symmetrical on the calves Individual lesions Nodules tending to ulcerate Course Lesions resolving slowly in month…