Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Satellite, in Transit, Regional, and Distant Metastases?

sentinel node biopsy was a useless exercise and doomed to the same ash-heap on which is strewn so many other egregious misconceptions about therapy for melanoma, ranging from amputation of limbs to the Miescher therapy with grenz rays for “len…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Junctional Activity and Active Junctional Nevus?

…tes with progressive descent into the dermis (both in terms of size of nests and size of nuclei) and nuclei of melanocytes monomorphic in nevi (except for Spitz nevi and ancient Mieschers nevi), in contrast to nuclei of melanocytes in melanoma…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

ABCDEs?

…#8220;ABCDE rule. According to the ABCDE rule, every pigmented skin lesion which is characterized by asymmetric configuration, irregular border, speckled color, diameter of more than 5 mm, and elevation should be prophylactically excised.” Brau…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Method for Surgery

…t it is a highly circumscribed one confined to what clinically seem to be benign, mostly exophytic growths such as warts, skin tags, seborrheic keratoses, and the melanocytic nevi of Unna and Miescher types. Those banal lesions may be removed in cosm…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…hair has been twisted back and forth. It does not, in itself, signify trichotillomania; sometimes patients twist a hair, to and fro, that emanates from a Mieschers nevus, for example, that hair inevitably showing evidence of trichomalacia. Th…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

…orically, histologically, clinically and molecularly, that the so-called dysplastic nevus is a type of melanocytic nevus and should be managed like other types of melanocytic nevi [1,2]. This reinforces the notion set forth by the late Bernie Ackerma…

Dermatology Practical & Conceptual

An atypical pigmented lesion on the nose

…with a paler, raised and scaly central area. [Copyright: ©2014 Savoia et al.] Dermatoscopy with a non-contact polarizing dermatoscope revealed an unspecific pattern, structureless and asymmetric (Figure 2), characterized by blue-gray radial lines, di…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wide and Deep Excision for Melanoma?

…James WD, Berger TG, Elston DM. Andrews’ Diseases of the Skin. 10th ed. Philadelphia. Elsevier Inc. 2006:699. “wide local excision radial margin was 1.4 cm (median, 1.0 cm)… lymphatic mapping and sentinel lymph node biopsies was su…