Histologic Diagnosis of Inflammatory Skin Diseases

Images

…s eosinophils are present in a thickened epidermis covered by scale-crust. At scanning magnification, aspects of pemphigus vulgaris are not apparent; higher magnification is required to detect them. 10.77.7A: Vesicular dermatitis, intraepiderma…

Dermatology Practical & Conceptual

From the Dermatologikum Hamburg: Quiz

…d partly ulcerated epidermis (Figure 2G) covered by extensive scale crust housing numerous neutrophils (Figure 2S). Some neutrophils are scattered within the epidermis (Figures 2D and 2H). A diffuse infiltrate of neutrophils, lymphocytes, plasma cell…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema marginatum

…esions that, at their periphery, are topped by collarettes of scale. Urticaria consists of evanescent edematous pink papules and/or plaques that usually are distributed widely and are pruritic. Findings histopathologic Fully developed Superficia…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

…iolaceous, or orange; the patches may be surmounted by a fine scale. A somewhat irregular or notched border may help differentiate early CTCL from clinically similar benign dermatoses, as may a discrete area of uninvolved skin within a larger lesion…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…layer (e.g., parakeratosis in mounds that house neutrophils, scale-crusts, hyphae). In regard to blistering diseases, an algorithm that achieves its purpose of enabling diagnosis accurately and with specificity can lead off with “vesicular der…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…ture of them histopathologically, e.g., “collarettes of scale” are indicative of parakeratosis propelled into being by spongiosis and having been shed, leaving behind only a tiny bit of it at the periphery, “apple jelly nodules&#822…

Differential Diagnosis in Dermatopathology

Pemphigus vulgaris vs. Grover’s disease, pemphigus vulgaris-like

…process being flaccid blisters that give way to erosions and crusts accompanied by erythema. When mostly the trunk is affected, the condition is termed “pemphigus foliaceus,” when mostly the face and upper part of the chest are involved,…

Differential Diagnosis in Dermatopathology

Psoriasis vs. Nummular dermatitis

…process being flaccid blisters that give way to erosions and crusts accompanied by erythema. When mostly the trunk is affected, the condition is termed “pemphigus foliaceus,” when mostly the face and upper part of the chest are involved,…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…sis Nummular Dermatitis 1. Confluent parakeratosis 1. Focal scale-crust 2. Granular zone mostly absent 2. Granular zone mostly present 3. Psoriasiform acanthosis with rete ridges of even length; some rete ridges thinned and some of those marked…