Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichenoid purpura (of Gougerot and Blum) Mycosis fungoides (plaque stage) 1. Epidermis usually normal or slightly acanthotic 1. Epidermis often psoriasiform 2. No lymphocytes disposed as solitary units in the epidermal basal layer 2. Lymphocyt…

Differential Diagnosis in Dermatopathology

Images

Lichenoid purpura (of Gougerot and Blum) Mycosis fungoides (plaque stage)…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphocytoma cutis

…atoid drug eruption
Lymphomatoid contact dermatitis
Lichenoid purpura of Gougerot and Blum
Various inflammatory diseases episodically, as dissimilar as psoriasis and dermatophytosis Findings histopathologic Simulators of B-cell lymphoma Fully develo…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid discoid lupus erythematosus

An inflammatory process, but not a vasculitis, that involves the legs especially with purpuric macules and subtle papules (Schamberg’s disease), lichenoid papules (lichenoid purpura of Gougerot-Blum), and scaly papules (eczematid-like purpura

Histologic Diagnosis of Inflammatory Skin Diseases

Cytomegalic inclusion disease

…dema and a moderately dense infiltrate of inflammatory cells. Purpura results from extravasation of erythrocytes in the dermis. Differential diagnosis histopathologic None exists. Findings in cytomegalic inclusion disease are distinctive. Laboratory…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen sclerosus et atrophicus

…ques associated often with telangiectasias and sometimes with purpura; resolving as white atrophic patches. Variations clinical Balanitis xerotica obliterans is lichen sclerosus et atrophicus on the glans penis; different names for the same process…

Dermatology Practical & Conceptual

What is your diagnosis? A solitary purple papule on the arm

The patient A 54-year-old woman with immune thrombocytopenic purpura (ITP) referred to our dermatology department with a three-week-history of a purple-colored lesion on her right arm. The patient was on treatment with oral prednisone at 20 mg/day f…