Differential Diagnosis in Dermatopathology

Discussions

Trichoepithelioma and infundibulocystic basal-cell carcinoma have many features in common, including relative symmetry, follicular differentiation, elements of both basaloid (trichoblastic) and squamoid (spinous) cells, necrotic neoplastic cells, mi…

Histologic Diagnosis of Inflammatory Skin Diseases

Darier’s disease and simulators of it

…er’s disease. Warty dyskeratoma, a type of infundibular cyst whose lining is characterized by changes throughout its circumference of acantholytic dyskeratosis, initially was called “isolated dyskeratosis follicularis,” implying a r…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Syringocystadenoma papilliferum Hidradenoma papilliferum 1. Not truly cystic (not a sac enclosed by epithelium) 1. Truly cystic (a sac enclosed completely or almost completely by epithelium) 2. Surface of skin papillated and hyperkeratotic 2….

Histologic Diagnosis of Inflammatory Skin Diseases

Linear IgA dermatosis

…tholytic dyskeratotic acanthoma, the distinctive infundibular cyst named, curiously, “warty dyskeratoma,” and the type of squamous-cell carcinoma designated “pseudoglandular.” In sum, acantholytic cells are not, themselves, di…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Dermatofibrosarcoma protuberans

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Differential Diagnosis in Dermatopathology

Discussions

…holytic dyskeratotic acanthoma), and an uncommon infundibular cyst (warty dyskeratoma). Those findings histopathologic occur also as an incidental change confined to a single rete ridge or even an infundibulum of a biopsy specimen that was taken for…

Dermatology Practical & Conceptual

Review of Practical Dermatopathology, 2nd edition by Ronald P. Rapini

…, elbow, lesions); some histological (e.g., hemosiderin, horn cyst, interstitial inflammation, acantholysis), etc. For each of these nonspecific and rather arbitrary characteristics, a list of entities/diseases is given—151 lists! The most frequent e…

Differential Diagnosis in Dermatopathology

Discussions

…times secondary to a ruptured infundibulum or an infundibular cyst. Therefore, the term dermatofibrosis describes the lesion more aptly, conveying as it does that the process is a type of fibrosing dermatitis, rather than a neoplasm of fibrocytes. Ma…

Differential Diagnosis in Dermatopathology

Trichoepithelioma vs. Infundibulocystic basal-cell carcinoma

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…