Differential Diagnosis in Dermatopathology

Discussions

Darier’s disease and Grover’s disease have several findings histopathologic in common, among them foci of acantholytic dyskeratotic cells in the epidermis and a superficial perivascular infiltrate of inflammatory cells, usually lymphocyt…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Dermatofibrosarcoma protuberans

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…stadenoma papilliferum Hidradenoma papilliferum 1. Not truly cystic (not a sac enclosed by epithelium) 1. Truly cystic (a sac enclosed completely or almost completely by epithelium) 2. Surface of skin papillated and hyperkeratotic 2. Surface of s…

Histologic Diagnosis of Inflammatory Skin Diseases

Darier’s disease and simulators of it

Darier’s disease and simulators of it Synonyms Darier-White disease Presentation stereotypical Age and sex Onset in childhood or adolescence in both sexes Distribution of lesions Symmetrical and widespread, favoring the neck, shoulders, upper…

Histologic Diagnosis of Inflammatory Skin Diseases

Linear IgA dermatosis

Linear IgA dermatosis Synonyms Linear IgA disease Chronic bullous disease of childhood Linear IgA bullous dermatosis Presentation stereotypical Age and sex Juvenile: onset in preschool children of both sexes; adult: in persons of both sexes Distribu…

Histologic Diagnosis of Inflammatory Skin Diseases

Keloid

Keloid Presentation stereotypical Age and sex Young adults especially, both sexes, more often in darkly pigmented individuals, especially Africans and African-Americans Distribution of lesions Sternal region, ear lobes, shoulders, and the upper part…

Differential Diagnosis in Dermatopathology

Discussions

Dermatofibroma and dermatofibrosarcoma protuberans are lesions made up of dense diffuse infiltrates of mesenchymal cells in company with bundles of collagen, the two together occupying at least much of the thickness of the dermis and sometimes part…

Differential Diagnosis in Dermatopathology

Trichoepithelioma vs. Infundibulocystic basal-cell carcinoma

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Dermatology Practical & Conceptual

Review of Practical Dermatopathology, 2nd edition by Ronald P. Rapini

The cover Figure 1. Rapini RP. Practical Dermatopathology. 2nd ed. Edinburgh : Elsevier, 2012. ISBN: 978-0-323-06658-7. 460 pages. $189.00. Review by François Milette I heartily recommend this book to pathologists and dermatologists looking for a…