Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Discussions

…o histopathologists as “intradermal nevus” (20% of specimens). The remarkably telangiectatic vessels of intradermal Spitz’s nevi causes them to be confused at times with vascular lesions such as hemangioma and pyogenic granuloma (20…

Histologic Diagnosis of Inflammatory Skin Diseases

Trichotillomania

…ted twisting to and fro. That finding alone, however, does not signify trichotillomania. For example, persons may twist in that manner a hair shaft that emerges from a congenital melanocytic nevus, especially of Mieschers type, and if that les

Differential Diagnosis in Dermatopathology

Verrucous seborrheic keratosis vs. Verrucous epidermal nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Discussions

…20;melanocytic nevus.” Melanocytic nevi may be acquired, such as those of Clark, Spitz, and Reed, or be congenital, such as those of Miescher and Unna, and a host of others named by ussuperficial,” “superficial and ‘de…

Differential Diagnosis in Dermatopathology

Pigmented Lesions

…) Proliferation of fibrocytes and histiocytes (lipophages and siderophages early in the course) in a mass in the reticular dermis, those cells appearing to be splayed between thickened bundles of collagen at the lateral margins. Melanin increased in…

Differential Diagnosis in Dermatopathology

See Classification of Pigmented Lesions

…igo Nevus of Ota, nevus of Ito Nevi Congenital Classic acral Superficial Superficial and “deep” Masson’s blue neuronevus Common blue (Jadassohn-Tieche) Combined Mieschers Unna’s Nevus spilus Persistent Special site Ye…

Dermatology Practical & Conceptual

An atypical pigmented lesion on the nose—Answer

…c pattern with the features of diffuse blue-gray pigmentation, scaling, polymorphic vessels and radial structures [1,6,8,9]. Congratulations to Dr. Paschal Dsouza, who was the first to send us the correct answer! References 1. Yoshida Y, Yamasaki A,…