Differential Diagnosis in Dermatopathology

Insect "bite" vs. Lymphomatoid papulosis

A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema. Wh…

Differential Diagnosis in Dermatopathology

Discussions

…icarial, often become vesicular, and of-times are covered by a crust. Because the lesions are so pruritic, evidences of excoriation in the form of erosions, ulcerations, and hemorrhagic crusts are expected. In contrast, papules of lymphomatoid papulo…

Histologic Diagnosis of Inflammatory Skin Diseases

Prurigo pigmentosa

Prurigo pigmentosa Synonym Nagashima’s disease Presentation stereotypical Age and sex Young women in the second and third decade of life are affected mostly; no family history is obtainable Distribution of lesions Symmetric on the trunk with p…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema multiforme

Erythema multiforme Synonyms Herpes iris Ectodermis erosive pluriorificialis Erytheme polymorphe Erythema multiforme exsudativum minor (Erythema multiforme minor, Erythema multiforme simplex, Erythema papulosum [Papular erythema multiforme]) Present…

Differential Diagnosis in Dermatopathology

Discussions

Early changes in papulonodular lesions of dermatofibromas are similar, in many respects, to those in Kaposi’s sarcoma. Both are dome-shaped and consist of proliferations that are highly cellular. Most of the cells are oval and they are joined…

Dermatology Practical & Conceptual

The dermatoscopic universe of basal cell carcinoma

…essels, keratin masses, white structureless areas, superficial scale, ulceration or blood crusts, blue-grey blotches and blood spots in keratin masses. Notably, nearly all BSC were reported to exhibit at least one BCC-related plus one SCC-related der…