Search Results for: scale-crust

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

…n CTCL, patches are often erythematous, but may be red-brown, violaceous, or orange; the patches may be surmounted by a fine scale. A somewhat irregular or notched border may help differentiate early CTCL from clinically similar benign dermatoses,…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…spongiosis, ballooning, acantholysis), and/or in the cornified layer (e.g., parakeratosis in mounds that house neutrophils, scalecrusts, hyphae). In regard to blistering diseases, an algorithm that achieves its purpose of enabling diagnosis…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema marginatum

…extremities of healthy adults and presents itself as annular lesions that, at their periphery, are topped by collarettes of scale. Urticaria consists of evanescent edematous pink papules and/or plaques that usually are distributed widely and are…

Differential Diagnosis in Dermatopathology

Discussions

…s. Papules that result from insect “bites” are urticarial, often become vesicular, and of-times are covered by a crust. Because the lesions are so pruritic, evidences of excoriation in the form of erosions, ulcerations, and hemorrhagic…

Metastatic papillary thyroid carcinoma to the nose mimicking basal cell carcinoma: report and review of cutaneous metastases of papillary thyroid cancer

Metastatic papillary thyroid carcinoma to the nose mimicking basal cell carcinoma: report and review of cutaneous metastases of papillary thyroid cancer

…telangiectatic nodule with central erosion on the right nasal tip (Figure 1). Microscopic examination of a 2 mm punch showed scale crust and parakeratosis overlying an atrophic epidermis. In the dermis, there were multiple nodules composed of large…

Histologic Diagnosis of Inflammatory Skin Diseases

Prurigo pigmentosa

…is en masse in foci Collections of neutrophils often found beneath a normal cornified layer with a basket-weave pattern Late Scalecrust that houses neutrophils Epidermis slightly acanthotic and parakeratotic Epidermis hyperpigmented Lymphocytes…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Psoriasis Nummular Dermatitis 1. Confluent parakeratosis 1. Focal scalecrust 2. Granular zone mostly absent 2. Granular zone mostly present 3. Psoriasiform acanthosis with rete ridges of even length; some rete ridges thinned and some of those…

Differential Diagnosis in Dermatopathology

Psoriasis vs. Nummular dermatitis

…inous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema. When mostly the trunk is affected, the condition is termed “pemphigus…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema multiforme

…ere in dark-skinned individuals Re-epithelialization of the epidermis beneath a subepidermal blister Slight parakeratosis or scalecrust sometimes Correlation clinicopathologic Macules result from spongiosis, ballooning, and a superficial…