Differential Diagnosis in Dermatopathology

Herpes simplex vs. Vaccinia

An inflammatory process characterized by a pruritic, papular, and, uncommonly, papulovesicular eruption of unknown cause affecting persons over 40 years of age (and usually over 60), often in photodistribution, but sometimes widespread. Although nam…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…olytic Dyskeratosis, e.g., Abscesses in Dermal Papillae and in Subepidermal Spaces, e.g., Dariers disease Dermatitis herpetiformis Grover’s disease Linear IgA dermatosis A type of epidermal nevus Acquired epidermolysis

Differential Diagnosis in Dermatopathology

Discussions

…a when widespread and ichthyosis hystrix when circumscribed in systematized fashion), and focal acantholytic dyskeratotic (so-called linear or systematized Dariers disease, a misnomer), in addition to the porokeratotic type under discussion he…

Differential Diagnosis in Dermatopathology

Discussions

Spongiotic dermatitis with discrete collections of cells in the epidermis and mycosis fungoides with discrete collections of cells in the epidermis (Pautrier’s “microabscesses”) share some findings histopathologic, including the pr…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema annulare centrifugum

Erythema annulare centrifugum Synonyms Erythema perstans Erythema gyratum perstans Erythema figuratum perstans Presentation stereotypical Age and sex Middle-aged or older adults of both sexes; children sometimes Distribution of lesions Any part of t…

Differential Diagnosis in Dermatopathology

Discussions

Tuberculoid leprosy and sarcoidosis are granulomatous dermatitides that resemble one another histopathologically because both consist of aggregations of epithelioid histiocytes in the dermis and, sometimes, in the subcutaneous fat. Despite the simil…

Histologic Diagnosis of Inflammatory Skin Diseases

Linear IgA dermatosis

…pecially the pustular expression), and dermatophytosis, and in suppurative infundibulitides of both infectious and noninfectious types. Acantholytic cells may be met with in diseases that are not strictly inflammatory, such as the genodermatosis Dari…

Differential Diagnosis in Dermatopathology

Discussions

…erpetiformis and herpes gestationis, neither of which has been shown to be viral in cause. When herpes simplex or zoster/varicella occurs in patients with other skin diseases such as atopic dermatitis and Dariers disease, spread fast of the in…

Differential Diagnosis in Dermatopathology

Images

Dariers disease (keratosis follicularis) Grover’s disease (transient acantholytic dermatosis)…

Differential Diagnosis in Dermatopathology

Tuberculoid leprosy vs. Sarcoidosis

An inflammatory process characterized by a pruritic, papular, and, uncommonly, papulovesicular eruption of unknown cause affecting persons over 40 years of age (and usually over 60), often in photodistribution, but sometimes widespread. Although nam…