Differential Diagnosis in Dermatopathology

Discussions

Tuberculoid leprosy and sarcoidosis are granulomatous dermatitides that resemble one another histopathologically because both consist of aggregations of epithelioid histiocytes in the dermis and, sometimes, in the subcutaneous fat. Despite the simil…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…olytic Dyskeratosis, e.g., Abscesses in Dermal Papillae and in Subepidermal Spaces, e.g., Dariers disease Dermatitis herpetiformis Grover’s disease Linear IgA dermatosis A type of epidermal nevus Acquired epidermolysis

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…eep form of pemphigus i.e., vulgaris, predominate; foci of the superficial form, i.e., foliaceus, rare 5. In a section from a single biopsy specimen, changes focal like those of Dariers disease, Hailey-Hailey disease, deep and superficial type…

Differential Diagnosis in Dermatopathology

Discussions

…erpetiformis and herpes gestationis, neither of which has been shown to be viral in cause. When herpes simplex or zoster/varicella occurs in patients with other skin diseases such as atopic dermatitis and Dariers disease, spread fast of the in…

Histologic Diagnosis of Inflammatory Skin Diseases

Pemphigus foliaceus

Pemphigus foliaceus Presentation stereotypical Age and sex Adults usually and of both sexes Distribution of lesions Localized to photodistribution in pemphigus erythematosus; widespread in pemphigus foliaceus Individual lesions Macules, patches, fla…

Histologic Diagnosis of Inflammatory Skin Diseases

Irritant contact dermatitis/Phototoxic dermatitis

…to being beneath the necrotic one by virtue of new basal cells supplied by infundibular epidermal and eccrine ductal keratocytes. Bibliography Bibliography for irritant contact dermatitis Darier J. Artificial dermatitides. In: Politzer S, ed. A Textb…

Differential Diagnosis in Dermatopathology

Pemphigus vulgaris vs. Grover’s disease, pemphigus vulgaris-like

…ertaking of this pocket atlas of dermatology? The reasons were several and varied, among them the following: 1.  Pictures are and always have been an extraordinarily valuable vehicle in the study of clinical dermatology. The first textbook of modern…

Histologic Diagnosis of Inflammatory Skin Diseases

Linear IgA dermatosis

…pecially the pustular expression), and dermatophytosis, and in suppurative infundibulitides of both infectious and noninfectious types. Acantholytic cells may be met with in diseases that are not strictly inflammatory, such as the genodermatosis Dari…

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular vasculitis

…ppson L. Ueber Phlebitis nodularis necroticans (Beitrag zu dem Studium der Tuberculides von Darier). Arch Dermatol Syphilol 1901; 55: 215–28. Whitfield A. On the nature of the disease known as erythema induratum scrofulosorum. Am J Med Sci 1901; 122:…

Differential Diagnosis in Dermatopathology

Discussions

Spongiotic dermatitis with discrete collections of cells in the epidermis and mycosis fungoides with discrete collections of cells in the epidermis (Pautrier’s “microabscesses”) share some findings histopathologic, including the pr…