Dermatology Practical & Conceptual

Pigmented poroma with unusual location and dermatoscopic features

…[5]. The differential diagnosis includes pyogenic granuloma, hemangioma, seborrheic keratosis, wart, fibroepithelial polyp, melanocytic nevus, cyst, BCC, squamous cell carcinoma and amelanotic melanomas [2,6]. Knowledge about the dermatoscopic featu…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Angiolymphoid Hyperplasia with Eosinophilia/Kimura’s Disease?

…d in the lesions, and was associated with various small round cell infiltrates and eosinophils. . . . Within the lesions, lymphoid follicles were prominent.” Kimura T, Yoshimura S, Ishikawa E. On the unusual granulation combined with hyperplast…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…from) + ptosis (a falling)]: Reputed to be a specific type of cell death in which dead cells are said to undergo fragmentation by implosion with subsequent phagocytosis of nuclear debris (Fig. 3.40). The process is claimed to occur in a wide variety…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Colors Stereotypical for Diseases Specific?

…rance of lymphangiomas and for the cherry red in that type of hemangioma known inaccurately as “senile.” It is important that dermatologists be alert to the effect of color of normal skin on the color of lesions cutaneous. For example, le…

Differential Diagnosis in Dermatopathology

Papular mucinosis vs Interstitial granuloma annulare

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular fasciitis

…al diagnosis histopathologic Fibrosarcoma exhibits abnormal spindle cells arranged in fascicles that tend to assume a herringbone pattern and does not display either abundant mucin or, as a finding consistent, an infiltrate of inflammatory cells….

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…11.18.1B: Large amount of mucin in company with scattered spindle- and stellate-shaped fibrocytes, as well as mast cells = Scleromyxedema, early ¬†This is an early lesion because mucin is so abundant in the reticular dermis. A synonym for the cond…

Differential Diagnosis in Dermatopathology

Morphea, late stage vs. Collagenous nevus

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…ump fibrocytes that act in a manner comparable to mesenchymal cells of a follicular papilla in an embryo, those cells bring forth the entire infundibulo-apocrine-sebaceous-follicular unit. Low-grade fibrosarcoma consists of abnormal spindle cells arr…