Clinical Case Studies

Progressive Ascending Telangiectasia

…A 49-year-old white female presented with widespread diffuse blue vessels on her lower extremities. The vessels appeared suddenly, 16 years after the birth of her third child. The vessels started on the feet and ankles, and progressed proximally ov…

Histologic Diagnosis of Inflammatory Skin Diseases

Gout

Gout Presentation stereotypical Age and sex Predominantly men Distribution of lesions Localized to ears and small joints, such as those of big toes Arrangement of lesions Discrete Individual lesions Papules, nodules, and even tumors Course Protracte…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

“An irreversible alopecia of the scalp occurs in negro women who straighten their hair with hot combs. The disease is common and distinctive, clinically and histopathologically. . . . Hot petrolatum used with the comb causes a chronic inflamm…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…n = Granuloma annulare Mucin in granuloma annulare usually is seen easily in sections stained by hematoxylin and eosin as blue-gray granular material, but it is colored a riveting aquamarine by the colloidal iron stain. In contrast to the situation…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…the dermoepidermal junction = Lupus erythematosus, discoid  A surfeit of mucin in the lower part of the reticular dermis is expected in many expressions cutaneous of lupus erythematosus, e.g., tumidus, profundus, and classic, on all sites anatomic,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

…egeneration and are dispatched from their site original to the skin surface, where they reside temporarily in a neutrophil-containing crust atop an ulcer. In sections stained by hematoxylin and eosin, degenerated bundles of collagen appear blue rathe…

Histologic Diagnosis of Inflammatory Skin Diseases

Reticulohistiocytic granuloma

…mpanied, nearly invariably, by a mix of inflammatory cells, as shown here. Bibliography Bibliography for reticulohistiocytic granuloma Allen AC. Survey of pathologic studies of cutaneous diseases during World War II. Arch Dermatol Syphilol 1946;57…