Dermatology Practical & Conceptual

An atypical pigmented lesion on the nose—Answer

Below find the answer and discussion to the quiz by Savoia et al. presented in the previous issue of Dermatology Practical & Conceptual (http://dx.doi.org/10.5826/dpc.0401a12). Diagnosis Pigmented cutaneous squamous cell carcinoma (PCSCC). Clini…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Method for Surgery

…egard to biopsy of inflammatory diseases that affect the nail unit, the following principles obtain: (1) as a rule, a specimen should be taken from the nail matrix; (2) when onychomycosis is suspected clinically, keratotic material situated beneath t…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…nd all epithelial structures of adnexa, i.e., hair follicles, sebaceous units, apocrine units, and eccrine units. Moreover, the vasculature and Schwann cells of nerves also are surrounded by a basement membrane. Figure 1.70 Basement membrane zone…

Dermatology Practical & Conceptual

Protecting the patient is our protection

Optimization and securing of medical practices and procedures has always been very challenging in medicine. However, the real-life clinical settings continue to pose various hazards that may lead medical professionals to unintended mistakes. Patholo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

…an increase in number of structurally normal melanocytes per unit area, which is associated with an irregular, uniform tan, freckle-like, gross lesion. This initial phase may be said to constitute the stage of premalignant hyperplasia (Stage I).&#82…

Dermatology Practical & Conceptual

An atypical pigmented lesion on the nose

The patient A 56-year-old Caucasian woman, with skin phototype III, presented with an asymptomatic, slow-growing, gray-black plaque on her nose. The lesion had appeared almost 6 months prior, was 10 x 5 mm in size and presented with a paler, raised…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

-oid?

…lzberger was at his prime and chairman of the Skin and Cancer Unit of New York University School of Medicine, the diagnosis of oid-oid disease (as it was known colloquially) was very popular among his many acolytes. When, however, Sulzberger left New…