Dermatology Practical & Conceptual

An atypical pigmented lesion on the nose

The patient A 56-year-old Caucasian woman, with skin phototype III, presented with an asymptomatic, slow-growing, gray-black plaque on her nose. The lesion had appeared almost 6 months prior, was 10 x 5 mm in size and presented with a paler, raised…

Dermatology Practical & Conceptual

An atypical pigmented lesion on the nose—Answer

Below find the answer and discussion to the quiz by Savoia et al. presented in the previous issue of Dermatology Practical & Conceptual (http://dx.doi.org/10.5826/dpc.0401a12). Diagnosis Pigmented cutaneous squamous cell carcinoma (PCSCC). Clini…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Method for Surgery

…egard to biopsy of inflammatory diseases that affect the nail unit, the following principles obtain: (1) as a rule, a specimen should be taken from the nail matrix; (2) when onychomycosis is suspected clinically, keratotic material situated beneath t…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…nd all epithelial structures of adnexa, i.e., hair follicles, sebaceous units, apocrine units, and eccrine units. Moreover, the vasculature and Schwann cells of nerves also are surrounded by a basement membrane. Figure 1.70 Basement membrane zone…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat

…or is not visualizable at all in a random section. The basic unit of the subcutaneous fat is a collection of adipocytes that seem to be cohesive, i.e., a primary microlobule. An aggregation of primary microlobules, termed a secondary lobule, is surr…

Dermatology Practical & Conceptual

Protecting the patient is our protection

Optimization and securing of medical practices and procedures has always been very challenging in medicine. However, the real-life clinical settings continue to pose various hazards that may lead medical professionals to unintended mistakes. Patholo…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…sts, but it differs by displaying many more of those foci per unit area of section of tissue. The lesion differs from Darier’s disease by the absence both of numerous discrete suprabasal clefts and of columns of parakeratosis. 10.45.3A: V…