Dermatology Practical & Conceptual

Strategies for early recognition of cutaneous melanoma-present and future

…localized in palmoplantar skin but may also involve the nail unit. ALM represents the most common growth variant in dark-skinned (e.g., Asian) populations. Due to the architecture of palmoplantar skin with parallel ridges and furrows, the margins ar…

Dermatology Practical & Conceptual

Dermoscopic clues to diagnose acantholytic dyskeratosis

Case presentations Case 1 A 61-year-old man presented with multiple small, reddish, eroded papules located on his chest (Figure 1A). Histopathologic examination revealed the typical findings of Grover’s disease. Figure 1. (A) Clinical examination…

Histologic Diagnosis of Inflammatory Skin Diseases

Introduction

…al components of the skin, namely, epidermis, hair follicles, sebaceous units, apocrine units, eccrine units, nail units, melanocytes, Langerhans” cells, Merkel cells, structures of the dermoepithelial interface, blood vessels, lymphatics, coll…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…nd all epithelial structures of adnexa, i.e., hair follicles, sebaceous units, apocrine units, and eccrine units. Moreover, the vasculature and Schwann cells of nerves also are surrounded by a basement membrane. Figure 1.70 Basement membrane zone…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Method for Surgery

…egard to biopsy of inflammatory diseases that affect the nail unit, the following principles obtain: (1) as a rule, a specimen should be taken from the nail matrix; (2) when onychomycosis is suspected clinically, keratotic material situated beneath t…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat

…or is not visualizable at all in a random section. The basic unit of the subcutaneous fat is a collection of adipocytes that seem to be cohesive, i.e., a primary microlobule. An aggregation of primary microlobules, termed a secondary lobule, is surr…

Dermatology Practical & Conceptual

An atypical pigmented lesion on the nose—Answer

Below find the answer and discussion to the quiz by Savoia et al. presented in the previous issue of Dermatology Practical & Conceptual (http://dx.doi.org/10.5826/dpc.0401a12). Diagnosis Pigmented cutaneous squamous cell carcinoma (PCSCC). Clini…

Dermatology Practical & Conceptual

Pre-emptive diagnosis of a case of scabies by dermatopathology

…elli H, Strub C, et al. Scabies outbreak in an intensive care unit with 1,659 exposed individuals-key factors for controlling the outbreak. Infect Control Hosp Epidemiol. 2009;30(4):354-60. CrossRef 4. Obasanjo OO, Wu P, Conlon M, et al. An outbrea…