Differential Diagnosis in Dermatopathology

Sebaceous hyperplasia vs. Nevus sebaceus of Jadassohn

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes on…

Differential Diagnosis in Dermatopathology

Discussions

…on, usually a man. Often it is misinterpreted clinically as a basal-cell carcinoma. Close inspection reveals a slightly dull-surfaced, violaceous, keratotic papule. The keratotic component militates against basal-cell carcinoma, a neoplasm whose surf…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…n planus-like keratosis often is misinterpreted clinically as basal-cell carcinoma, it sometimes, albeit uncommonly, is removed by complete excision, as was the case here. As a rule, the lesion is shaved off superficially. Note at scanning magnificat…

Histologic Diagnosis of Inflammatory Skin Diseases

Radiation dermatitis and panniculitis

…se Protracted Variations clinical Malignant neoplasms such as basal-cell carcinoma, squamous-cell carcinoma, melanoma, fibrosarcoma, and malignant fibrous histiocytoma may develop in zones of radiation sclerosis. Differential diagnosis clinical Morph…

Differential Diagnosis in Dermatopathology

Discussions

…f sebaceous hyperplasia may be misinterpreted clinically as a basal-cell carcinoma because both conditions have a slightly elevated border and a central dell. In basal-cell carcinoma, however, the depression in the center usually represents an erosio…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

…eoplasia with cytomorphologic features of malignancy, namely, carcinoma in situ lesions, by surgical pathologists. If one looks for an equivalent lesion to the so-called dysplastic (carcinoma in situ) lesions of epithelial tissue in melanocytic neopl…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…llagen in the upper part of the dermis, of lymphocytes in the basal layer, and of elongated mounds of parakeratosis militate against that diagnosis. 10.80.2A: Perivascular dermatitis, slightly spongiotic + 10.80.2B: Lymphocytes in the basal