Differential Diagnosis in Dermatopathology

Sebaceous hyperplasia vs. Nevus sebaceus of Jadassohn

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes on…

Differential Diagnosis in Dermatopathology

Discussions

…son, usually a man. Often it is misinterpreted clinically as a basal-cell carcinoma. Close inspection reveals a slightly dull-surfaced, violaceous, keratotic papule. The keratotic component militates against basal-cell carcinoma, a neoplasm whose sur…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…en planus-like keratosis often is misinterpreted clinically as basal-cell carcinoma, it sometimes, albeit uncommonly, is removed by complete excision, as was the case here. As a rule, the lesion is shaved off superficially. Note at scanning magnifica…

Differential Diagnosis in Dermatopathology

Discussions

…of sebaceous hyperplasia may be misinterpreted clinically as a basal-cell carcinoma because both conditions have a slightly elevated border and a central dell. In basal-cell carcinoma, however, the depression in the center usually represents an erosi…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

Editorial In a recent two-part essay entitled “The dysplastic nevus: from historical perspective to management in the modern era” published in the Journal of American Academy of Dermatology, Duffy and Grossman concluded, following compre…

Histologic Diagnosis of Inflammatory Skin Diseases

Radiation dermatitis and panniculitis

…arsenical keratosis, all three being superficial squamous-cell carcinomas. Basal-cell carcinomas also develop in chronic radiodermatitis, as do melanomas and sarcomas (so-called radiation sarcomas). The changes just enumerated that develop in the de…

Histologic Diagnosis of Inflammatory Skin Diseases

Pityriasis rubra pilaris

…dibula dilated and plugged by orthokeratotic and parakeratotic cells in a manner similar to that in the epidermis Late All the findings in lesions developed fully, except mitotic figures are not present above the basal layer, and there is no pallor…