Histologic Diagnosis of Inflammatory Skin Diseases

Images

…en planus-like keratosis often is misinterpreted clinically as basal-cell carcinoma, it sometimes, albeit uncommonly, is removed by complete excision, as was the case here. As a rule, the lesion is shaved off superficially. Note at scanning magnifica…

Histologic Diagnosis of Inflammatory Skin Diseases

Radiation dermatitis and panniculitis

…arsenical keratosis, all three being superficial squamous-cell carcinomas. Basal-cell carcinomas also develop in chronic radiodermatitis, as do melanomas and sarcomas (so-called radiation sarcomas). The changes just enumerated that develop in the de…

Differential Diagnosis in Dermatopathology

Discussions

…of sebaceous hyperplasia may be misinterpreted clinically as a basal-cell carcinoma because both conditions have a slightly elevated border and a central dell. In basal-cell carcinoma, however, the depression in the center usually represents an erosi…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

Editorial In a recent two-part essay entitled “The dysplastic nevus: from historical perspective to management in the modern era” published in the Journal of American Academy of Dermatology, Duffy and Grossman concluded, following compre…

Histologic Diagnosis of Inflammatory Skin Diseases

Pityriasis rubra pilaris

…dibula dilated and plugged by orthokeratotic and parakeratotic cells in a manner similar to that in the epidermis Late All the findings in lesions developed fully, except mitotic figures are not present above the basal layer, and there is no pallor…

Histologic Diagnosis of Inflammatory Skin Diseases

Blood Vessels

…lectron microscopy to consist of a single layer of endothelial cells that line a narrow lumen, those cells being surrounded by a layer of pericytes (Fig. 1.78). The endothelial cells and pericytes are enveloped by a basal lamina. In the descending ve…