Differential Diagnosis in Dermatopathology

Papular mucinosis vs Interstitial granuloma annulare

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Differential Diagnosis in Dermatopathology

Pigmented Lesions

…507, 508, 509) An epidermis thickened by two populations of cells, namely, pigmented “basaloid” ones with scant cytoplasm that make up the bulk of the lesion and nearly non-pigmented “squamoid” cells with copious cytoplasm…

Differential Diagnosis in Dermatopathology

Discussions

…during the histiocytic phase of dermatofibroma, “monster cells” may be present in abundance, those nuclei of histiocytes being very large and very pleomorphic, akin to those of malignant fibrous histiocytoma. The nuclei of the neoplastic…

Differential Diagnosis in Dermatopathology

Discussions

In addition to possessing some cells with extraordinarily atypical nuclei, those referred to colloquially as “monster” cells, the two pathologic processes of very different nature that are the basis for this particular exercise in differ…

Differential Diagnosis in Dermatopathology

Angiolymphoid hyperplasia with eosinophilia vs. Kimura’s disease

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Differential Diagnosis in Dermatopathology

Discussions

…phocytes and eosinophils, possess vessels lined by endothelial cells that may be plump and contain abundant cytoplasm, display fibroplasia, exhibit many plasma cells, and spare epithelial and non-epithelial structures of adnexa. Despite these element…

Dermatology Practical & Conceptual

Melanoma and satellite blue papule

…seborrheic keratosis, including lichen planus-like keratosis, hemangioma, pigmented basal cell carcinoma, hemosiderotic dermatofibroma, Kaposi sarcoma and angiosarcoma. Finally, exogenous dermal blue pigmentation, such as ink tattoo, radiation tatto…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Dermatofibrosarcoma protuberans

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Differential Diagnosis in Dermatopathology

Dermatofibroma with "monster" cells vs. Malignant fibrous histiocytoma

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….