Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

“Parapsoriasis. Under this provisional name, Brocq in 1902 grouped several rare and unclassifiable dermatological types, characterized by nonpruriginous erythmato-squamous spots, extremely persistent and rebellious to all treatment. It is ex…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…erences between them histopathologically, namely, inflammatory cells around follicles and irregular epidermal growth in the former, and inflammatory cells only in dermal papillae with partial atrophy of the epidermis in the latter. In the same articl…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.86.1A: Perivascular dermatitis, lymphocytic + 10.86.1B: Thin cornoid lamella = Porokeratosis, disseminated superficial actinic  The cornoid lamella on the left springs from an infundibulum. Cornoid lamellae also may emanate from…

Differential Diagnosis in Dermatopathology

Discussions

…yringeal segments of eccrine ducts and, therefore, consists of cells that line those ducts (cuticular cells), of the cells immediately peripheral to lining cells (poroid cells), and of tubules themselves. Most eccrine poromas protrude from the epider…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.43.1A: Nodular dermatitis, granulomatous + 10.43.1B: Interstitial and palisaded array of histiocytes around loci of deposits of mucin and degeneration of collagen = Granuloma annulare This is a presentation stereotypical of gran…

Histologic Diagnosis of Inflammatory Skin Diseases

Polymorphous light eruption

Polymorphous light eruption Synonyms Polymorphic light eruption Summer prurigo Summer eruption Eczema solare Prurigo aestivalis Chronic polymorphous light eruption Hutchinson’s summer prurigo Presentation stereotypical Age and sex Young wome…

Histologic Diagnosis of Inflammatory Skin Diseases

Photoallergic dermatitis

Photoallergic dermatitis Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Sites exposed to sunlight especially, i.e., the face, the V region of the chest, forearms, and dorsa of hands; covered sites affected someti…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

Granuloma annulare Presentation stereotypical Age and sex Any age in both sexes Distribution of lesions Localized, often to extensor aspects of extremities, or widespread Configuration of lesions Annular, sometimes arcuate Arrangement of lesions Sca…

Histologic Diagnosis of Inflammatory Skin Diseases

Our Definition of “Inflammation” and “Inflammatory Disease”

…pathologically by vasodilation and infiltrates of inflammatory cells, those especially being neutrophils, eosinophils, lymphocytes, plasma cells, and histiocytes. Inflammatory Disease. A disorder characterized histopathologically by an infiltrate o…

Histologic Diagnosis of Inflammatory Skin Diseases

Miescher’s granuloma of the face

…lare spectrum. Arch Dermatol 1973;107:62–64. O’Brien JP. Actinic granuloma. An annular connective tissue disorder affecting sun- and heat-damaged (elastotic) skin. Arch Dermatol 1975;111:460–66. Steffen C. Actinic granuloma (O’Brien). J C…