Dermatology Practical & Conceptual

Strategies for early recognition of cutaneous melanoma-present and future

…criteria corresponded to the presence of atypical melanocytic cells within the epidermal basal layer and the papillary dermis or within the basal layer of non-edged papillae. The four minor criteria were represented by the presence of roundish cells…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…erences between them histopathologically, namely, inflammatory cells around follicles and irregular epidermal growth in the former, and inflammatory cells only in dermal papillae with partial atrophy of the epidermis in the latter. In the same articl…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

“Parapsoriasis. Under this provisional name, Brocq in 1902 grouped several rare and unclassifiable dermatological types, characterized by nonpruriginous erythmato-squamous spots, extremely persistent and rebellious to all treatment. It is ex…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…cally looks like a cloak composed of cords of undifferentiated cells is seen in sections oriented horizontally to be a skirt that encircles the follicle. At puberty, in response to endogenous androgens, those undifferentiated epithelial cells prolife…

Differential Diagnosis in Dermatopathology

Discussions

…hat begin in the epidermis. Whereas Bowen’s disease is a squamous-cell carcinoma (it cornifies), extramammary Paget’s disease is an apocrine carcinoma (it consists of neoplastic apocrine cells and sometimes attempts to form acine). Despit…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.86.1A: Perivascular dermatitis, lymphocytic + 10.86.1B: Thin cornoid lamella = Porokeratosis, disseminated superficial actinic ┬áThe cornoid lamella on the left springs from an infundibulum. Cornoid lamellae also may emanate from…

Differential Diagnosis in Dermatopathology

Discussions

…yringeal segments of eccrine ducts and, therefore, consists of cells that line those ducts (cuticular cells), of the cells immediately peripheral to lining cells (poroid cells), and of tubules themselves. Most eccrine poromas protrude from the epider…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.43.1A: Nodular dermatitis, granulomatous + 10.43.1B: Interstitial and palisaded array of histiocytes around loci of deposits of mucin and degeneration of collagen = Granuloma annulare This is a presentation stereotypical of gran…

Histologic Diagnosis of Inflammatory Skin Diseases

Polymorphous light eruption

Polymorphous light eruption Synonyms Polymorphic light eruption Summer prurigo Summer eruption Eczema solare Prurigo aestivalis Chronic polymorphous light eruption Hutchinson’s summer prurigo Presentation stereotypical Age and sex Young wome…

Histologic Diagnosis of Inflammatory Skin Diseases

Photoallergic dermatitis

Photoallergic dermatitis Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Sites exposed to sunlight especially, i.e., the face, the V region of the chest, forearms, and dorsa of hands; covered sites affected someti…