Dermatology Practical & Conceptual

Strategies for early recognition of cutaneous melanoma-present and future

…iple colors (black, brown, white). The surrounding skin shows actinic damage. [Copyright: ©2012 Brehmer et al.] Figure 2. A nodular melanoma (NM) that developed secondarily within a superficial spreading melanoma on the back (Breslow thickness 3.5…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…ebaceous gland marks the site where lipid-producing glandular cells of sebaceous lobules meet stratified squamous epithelium of an infundibulum. A sebaceous duct is lined by a thin cornifying squamous epithelium with a barely detectable granular zone…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…e perivascular and periadnexal infiltrate with numerous giant cells in the “subpapillary portion of the corium.” The infiltrate also was situated in dermal papillae, around eccrine glands, and in adipose tissue. The extensions of follicul…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

…rmatological types, characterized by nonpruriginous erythmato-squamous spots, extremely persistent and rebellious to all treatment. It is exclusively the objective appearance of these dermatoses which led to their mutual approximation to psoriasis. T…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…hin cornoid lamella = Porokeratosis, disseminated superficial actinic  The cornoid lamella on the left springs from an infundibulum. Cornoid lamellae also may emanate from eccrine ducts or surface epidermis itself. The condition was named porokeratos…

Differential Diagnosis in Dermatopathology

Discussions

…hologic develop in them. Those range from formation of “squamous eddies” to development of nuclear abnormalities that may simulate vaguely the kind seen in squamous-cell carcinoma. Of the three major patterns of seborrheic keratoses, name…

Histologic Diagnosis of Inflammatory Skin Diseases

Polymorphous light eruption

…extent of exposure to ultraviolet light Variations clinical Actinic prurigo is a type of polymorphous light eruption that occurs in Indians of North and South America. Spring eruption of juveniles consists of vesicles on helices of boys. Different…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…that happens, the condition should not then be called “actinic granuloma”; it still is granuloma annulare. 10.43.7A: Nodular dermatitis, granulomatous + 10.43.7B: Histiocytes in palisaded array around a locus replete with mucin…

Histologic Diagnosis of Inflammatory Skin Diseases

Photoallergic dermatitis

…rubbing intensively and persistently, which is exemplified by actinic reticuloid. Differential diagnosis clinical Allergic contact dermatitis caused by airborne allergens may be indistinguishable, sparing as it does the submental region and skin…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

…it has been accorded a place apart in this subchapter. “Actinic granuloma” consists of annular plaques of granuloma annulare situated on skin damaged badly by sunlight. Differential diagnosis clinical Sarcoidosis may be annular, especia…