Search Results for: morpheiform basal-cell carcinoma

Histologic Diagnosis of Inflammatory Skin Diseases

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….80.3A: Perivascular dermatitis, slightly spongiotic + 10.80.3B: A few lymphocytes along the dermoepidermal junction, in the basal layer, and in the spinous zone in association with paltry spongiosis = Pityriasis alba Although the changes shown at…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo?

…0;The solar lentigo shows epidermal hyperplasia with elongation of the rete pegs and melanocytic hyperplasia confined to the basal cell layer.” Farmer ER, Hood AF. Melanocytic tumors. In: Farmer ER, Hood AF, eds. Pathology of the Skin. New…

Differential Diagnosis in Dermatopathology

Guttate psoriasis vs. Guttate (dermatosis) parapsoriasis

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Acquired Epidermolysis Bullosa?

…: 1. The finding of IgG at the BMZ by direct immunofluorescence microscopy 2. Demonstration of blister formation beneath the basal lamina, which remains on the epidermal side of the blister by electron microscopy 3. Deposition of IgG in the…

Histologic Diagnosis of Inflammatory Skin Diseases

Epidermolysis bullosa simplex

…y developed Dermal papillae preserved beneath what seems, at first blush, to be a subepidermal blister Vacuoles in epidermal basal cells at the sides of the blister Clefts cut a swath through epidermal basal cells Little or no infiltrate of…

Melanoma arising in a giant nevus spilus maculosus

Melanoma arising in a giant nevus spilus maculosus

…unch biopsy of the speckled lentiginous nevus. The biopsy was taken from the thigh. Mild acanthosis and hyperpigmentation of basal keratinocytes is present but there is no marked proliferation of melanocytes. Figures 6A-G. Histopathology of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…est, which gives rise to dorsal root and sympathetic ganglia, and to their nerve processes, Schwann cells, endoneural sheath cells, and laminar cells of specialized sensory end organs. Nerves in the reticular dermis travel along the course of the…

Differential Diagnosis in Dermatopathology

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Metastatic carcinoma from a breast Morpheiform basal-cell carcinoma

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Metastatic carcinoma from a breast Morpheiform basalcell carcinoma 1. Strands, cords, and columns of neoplastic epithelial cells in the dermis 1. Cords and columns of neoplastic epithelial cells in the dermis; no strands as a rule 2….

Differential Diagnosis in Dermatopathology

Erythroderma of psoriasis vs. Erythroderma of mycosis fungoides

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes…