Differential Diagnosis in Dermatopathology

Discussions

…hocytes and eosinophils, possess vessels lined by endothelial cells that may be plump and contain abundant cytoplasm, display fibroplasia, exhibit many plasma cells, and spare epithelial and non-epithelial structures of adnexa. Despite these elements…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…11.16.2B: Proliferation of small vessels, edema, a mixed-cell infiltrate, and a thinned epidermis = Pyogenic granuloma, fully developed  At the base of the section is a large muscle-containing vessel that spiraled upward and from which sprang th…

Differential Diagnosis in Dermatopathology

Dermatofibroma with "monster" cells vs. Malignant fibrous histiocytoma

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Histologic Diagnosis of Inflammatory Skin Diseases

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Dermatofibrosarcoma protuberans

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Differential Diagnosis in Dermatopathology

Angiolymphoid hyperplasia with eosinophilia vs. Kimura’s disease

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Dermatology Practical & Conceptual

Melanoma and satellite blue papule

…seborrheic keratosis, including lichen planus-like keratosis, hemangioma, pigmented basal cell carcinoma, hemosiderotic dermatofibroma, Kaposi sarcoma and angiosarcoma. Finally, exogenous dermal blue pigmentation, such as ink tattoo, radiation tattoo…

Differential Diagnosis in Dermatopathology

Pyogenic granuloma vs. Bacillary angiomatosis

A systemic disease, which manifests itself in the skin first as violaceous macules and patches that tend to progress to papules and plaques, and sometimes to nodules and tumors, all of which represent hyperplasia of endothelial cells….

Differential Diagnosis in Dermatopathology

Discussions

…e lesions made up of dense diffuse infiltrates of mesenchymal cells in company with bundles of collagen, the two together occupying at least much of the thickness of the dermis and sometimes part of the subcutaneous fat. Nuclei are not atypical as a…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…n, but not acanthotic at the periphery of it 3. No nests of cells in the dermis 3. Nests of cells in the dermis 4. Stellate, oval, spindle-shaped, and round cells (fibrocytes and histiocytes); no polygonal cells 4. Polygonal cells (abnormal melan…