Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…cally looks like a cloak composed of cords of undifferentiated cells is seen in sections oriented horizontally to be a skirt that encircles the follicle. At puberty, in response to endogenous androgens, those undifferentiated epithelial cells prolife…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

“Parapsoriasis. Under this provisional name, Brocq in 1902 grouped several rare and unclassifiable dermatological types, characterized by nonpruriginous erythmato-squamous spots, extremely persistent and rebellious to all treatment. It is ex…

Differential Diagnosis in Dermatopathology

Trichoblastoma, small nodular type vs. Trichoblastoma, large nodular type

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque, a…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…12B: A band of histiocytes, some of them multinucleate, around squamous epithelium that, in turn, surrounds cellulose = Foreign body reaction to a splinter The splinter came to be surrounded by squamous epithelium by virtue of epidermis, either surfa…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidermal Cyst and Epidermoid Cyst?

“Epidermoid cyst. Synonym: Sebaceous cyst, steatoma, epithelial cyst. Definition: A cyst containing keratin and its breakdown products, surrounded by an epidermoid wall.” Mackie RM. Epidermal skin tumors. In: Champion RH, Burton JL, Eb…