Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Spongiform Pustular Diseases?

“The pustule I have designated spongiform (spongelike) was markedly and impressively seen in acrodermatitis continua of Hallopeau. It is composed of leukocytes that have migrated into the soaked epidermis, destroying epithelial cells by inva…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…i in the lumen in the context of an infiltrate of inflammatory cells. In the vast majority of instances, the cells are neutrophils, e.g., in leukocytoclastic vasculitis, septic vasculitis, and livedo vasculitis. Rarely, lymphocytes monopolize the inf…

Differential Diagnosis in Dermatopathology

Discussions

…clear abnormalities that may simulate vaguely the kind seen in squamous-cell carcinoma. Of the three major patterns of seborrheic keratoses, namely, acanthotic, adenoid (reticulate), and verrucous, only the acanthotic type presents a problem in diffe…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…cally looks like a cloak composed of cords of undifferentiated cells is seen in sections oriented horizontally to be a skirt that encircles the follicle. At puberty, in response to endogenous androgens, those undifferentiated epithelial cells prolife…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

“Parapsoriasis. Under this provisional name, Brocq in 1902 grouped several rare and unclassifiable dermatological types, characterized by nonpruriginous erythmato-squamous spots, extremely persistent and rebellious to all treatment. It is ex…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…erences between them histopathologically, namely, inflammatory cells around follicles and irregular epidermal growth in the former, and inflammatory cells only in dermal papillae with partial atrophy of the epidermis in the latter. In the same articl…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…12B: A band of histiocytes, some of them multinucleate, around squamous epithelium that, in turn, surrounds cellulose = Foreign body reaction to a splinter The splinter came to be surrounded by squamous epithelium by virtue of epidermis, either surfa…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidermal Cyst and Epidermoid Cyst?

“Epidermoid cyst. Synonym: Sebaceous cyst, steatoma, epithelial cyst. Definition: A cyst containing keratin and its breakdown products, surrounded by an epidermoid wall.” Mackie RM. Epidermal skin tumors. In: Champion RH, Burton JL, Eb…