Histologic Diagnosis of Inflammatory Skin Diseases

Images

…the extent of the hyperkeratosis, the hypergranulosis, and the acanthosis. 10.60.19A: Perivascular dermatitis, lichenoid, peri-infundibulitis, and perifolliculitis + 10.60.19B: Lymphocytes, jagged acanthosis, wedge-shaped hypergranulosis, a…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…er in some examples of lichen simplex chronicus. Figure 3.4 Acanthosis. Acanthosis is an attribute of diseases such as psoriasis and of psoriasiform dermatitides such as pityriasis rubra pilaris and longstanding examples of allergic contact dermat…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Persistent light reaction

Persistent light reaction Synonyms Actinic reticuloid, chronic actinic dermatitis, chronic photosensitive dermatitis, photosensitive eczema Presentation stereotypical Age and sex Men especially Distribution of lesions Sun-exposed sites, i.e., the fa…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

Lichen planus Synonyms Lichen ruber planus Lichen ruber Presentation stereotypical Age and sex More common in women, especially young and middle-aged adults Distribution of lesions Flexor surface of forearms and wrists, but no site is exempt. Occu…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.81.1A: Perivascular dermatitis, spongiotic + 10.81.1B: Lymphocytes in an edematous papillary dermis and in spongiotic foci of a slightly acanthotic, hyperkeratotic epidermis, erythrocytes being extravasated in both the dermis an…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.20.1A: Nodular dermatitis, granulomatous + 10.20.1B: Numerous extravasated erythrocytes, siderophages, and fibrocytes = Dermatofibroma An important finding for diagnosis of a dermatofibroma such as this one is seen at the periph…

Histologic Diagnosis of Inflammatory Skin Diseases

Pityriasis rubra pilaris

Pityriasis rubra pilaris Synonyms Pityriasis pilaris Presentation stereotypical Age and sex Adults in about the fifth decade of life and children in the first 5 years of life; same frequency in both sexes Distribution of lesions Symmetric and widesp…