Differential Diagnosis in Dermatopathology

Discussions

Trichoadenoma and microcystic adnexal carcinoma at times resemble each other sufficiently to pose a dilemma diagnostic, even though the former is a hamartoma and the latter an adenocarcinoma. Both may have several findings histopathologic in common:…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine Neoplasms?

Classification of Skin Appendage Tumors Eccrine Differentiation Eccrine nevus Eccrine duct proliferation Eccrine-centered nevus Eccrine angiomatous hamartoma Syringofibroadenoma or acrosyringeal nevus Comedo nevus of the palm, linear eccrine nevu…

Differential Diagnosis in Dermatopathology

Trichoadenoma vs. Microcystic adnexal carcinoma

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Differential Diagnosis in Dermatopathology

Discussions

In general, neoplasms metastatic to the skin present little difficulty in differential diagnosis from neoplasms primary in the skin. Carcinoma of the breast is an exception. If there are but a few neoplastic cells and numerous inflammatory cells sca…

Differential Diagnosis in Dermatopathology

Discussions

Nevus verrucosus and acanthosis nigricans are processes that affect the papillary dermis and the epidermis. Both conditions may display hyperkeratosis, epidermal hyperpigmentation, papillomatosis, melanophages, and an increased number of fibrocytes…