Differential Diagnosis in Dermatopathology

Discussions

…stic, even though the former is a hamartoma and the latter an adenocarcinoma. Both may have several findings histopathologic in common: presence of infundibular cyst-like structures scant stroma, epithelial components connected to pre-existing normal…

Differential Diagnosis in Dermatopathology

Trichoadenoma vs. Microcystic adnexal carcinoma

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine Neoplasms?

…arcinoma) Polymorphous sweat gland carcinoma Digitalpapillary adenocarcinoma Malignant cylindroma Malignant spiradenoma (spiradenocarcinoma) Porocarcinoma Squamoid eccrine ductal carcinoma Miscellaneous sweat gland carcinomas David Weedon. Skin Path…

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

Pigmented plaques formed by confluence of smooth-surfaced soft papules, some of which may become polypoid, traversed by accentuations of skin folds. This disease has a predilection for intertriginous regions. The condition may develop consequent to…

Differential Diagnosis in Dermatopathology

Discussions

…structures of syringomas, however, unlike those in metastatic adenocarcinoma, often show comma-like extensions that have been compared to the shape of a tadpole. Cornifying cysts and calcification are common features of syringoma, but not, as a rule,…

Differential Diagnosis in Dermatopathology

Discussions

…ous manifestation of an occult malignant neoplasm, usually an adenocarcinoma of the gastrointestinal or genital tract, breast, or lung (“malignant” acanthosis nigricans). Each of these forms of acanthosis nigricans, irrespective of the un…