Therapeutic Strategies in Dermatology

Lichen Planus: Clinical Cases

Clinical Cases Case 1 Generalized cutaneous and mucosal lichen planus 53-year-old man with hepatitis C viral infection Acute onset of intensely pruritic, purpuric, papular eruption No constitutional symptoms Initial evaluation Bilateral…

Therapeutic Strategies in Dermatology

Superficial Fungal Infections: Clinical Cases

Clinical Cases Case 1 Onychomycosis and tinea pedis 47-year-old healthy male with long-standing itching and rash on the soles of bilateral feet, with dystrophic toenails He has used over-the-counter cream for athlete¬í’s foot, which part…

Therapeutic Strategies in Dermatology

Viral Exanthems: Initial Evaluation

Initial Evaluation Patients with a viral exanthem often present with a non-specific morbilliform eruption. In some cases, the skin disease as part of a constellation of other symptoms may indicate a specific viral etiology. Measles German m…

Therapeutic Strategies in Dermatology

Lichen Planus: Key Points

Key Points Lichen planus (LP) is a pruritic eruption that may be self-limited or chronic, and may affect skin, mucosa (including the esophagus), and hair. The classic morphology of lichen planus is violaceous-to-purple, flat-topped polygonal papule…

Therapeutic Strategies in Dermatology

Acne Vulgaris: Treatment

Treatment Mild to moderate acne First-line therapy (comedonal acne only): topical retinoid First-line therapy (mild inflammatory acne): topical retinoid alone, topical retinoid + topical antimicrobial Topical retinoids are considered first…

Therapeutic Strategies in Dermatology

Lupus: Key Points

Key Points Lupus is a disease that presents across a broad spectrum of cutaneous and systemic manifestations. It may be cutaneous-only or systemic with cutaneous manifestations; some patients with systemic lupus do not have cutaneous involvement. D…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Key Points

Key Points The treatment of syphilis is based on the duration of infection and the organ systems involved. Five subtypes of syphilis can be distinguished: primary, secondary, or early syphilis of less than 1 year’s duration; infection of inde…

Histologic Diagnosis of Inflammatory Skin Diseases

Traction alopecia

Traction alopecia Synonyms Hot comb alopecia Follicular degeneration syndrome Presentation stereotypical Age and sex Young women, especially African-Americans Distribution of lesions Scalp, in symmetrical fashion, particularly along the frontal ha…

Histologic Diagnosis of Inflammatory Skin Diseases

Alopecia areata, totalis, universalis

…(totalis), or be universal (universalis) Variations clinical Alopecia areata consists of one or more discrete bald patches. Alopecia totalis affects the entire scalp, which is hairless. Alopecia universalis is marked by loss of all body hair. Ophia…

Differential Diagnosis in Dermatopathology

Trichotillomania (developed fully) vs. Traction alopecia (end stage)

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that be…