Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Differential Diagnosis in Dermatopathology

Discussions

At first glance, a reader might think an error previous has been made because the two columns preceding are identical, but that was done deliberately; lichen sclerosis et atrophicus is superficial morphea. Morphea is one of the sclerodermas and lich…

Differential Diagnosis in Dermatopathology

Lichen sclerosus et atrophicus vs. Superficial morphea

A generic term for at least two different inflammatory diseases that have in common hardening of the skin by virtue of thickening of bundles of collagen in the dermis and subcutis. One of those diseases manifests itself as localized or widespread pa…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Scleroderma?

“Scleroderma is a chronic disease of unknown cause that affects the microvasculature and loose connective tissue and is characterized by fibrosis and obliteration of vessels in the skin, lungs, gastrointestinal tract, kidneys and heart. It m…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

Lipodystrophy Synonyms Lipoatrophy Wucher atrophy Presentation stereotypical Age and sex Females, first decade of life Distribution of lesions Upper half of body in the “partial” expression of the process and widespread in the “t…

Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis chronica atrophicans

Acrodermatitis chronica atrophicans Presentation stereotypical Age and sex Middle aged to elderly women especially Distribution of lesions Distal part of extremities, particularly of legs; nodules develop especially near knees and elbows Configurati…

Histologic Diagnosis of Inflammatory Skin Diseases

Keratosis pilaris/Lichen spinulosus

Keratosis pilaris/Lichen spinulosus Presentation stereotypical Age and sex Adolescents especially, females more than males Distribution of lesions Primarily extensor surfaces Configuration of lesions Circular in lichen spinulosus Arrangement of lesi…

Differential Diagnosis in Dermatopathology

Lupus profundus vs. Morphea profundus

A generic term for at least two different inflammatory diseases that have in common hardening of the skin by virtue of thickening of bundles of collagen in the dermis and subcutis. One of those diseases manifests itself as localized or widespread pa…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

Degos’ disease (malignant atrophic papulosis) Synonyms Degos’ syndrome Malignant atrophic papulosis Papulosis atrophicans maligna Koehlmeier-Degos syndrome Thromboangiitis cutaneointestinalis disseminata Fatal cutaneointestinal syndrome…