Search Results for: b-cell lymphocytic leukemia

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

…as a papule or nodule which may become ulcerated. On the basis of clinico-pathologic correlation, five distinctive types of basal cell carcinoma have been identified, namely, nodular, superficial, morpheiform, fibroepithelial, and…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

…umors, sometimes solitary but at other times numerous, and often in clusters on any anatomic site. When “primary,” Bcell lymphomas of the skin seem to be wholly cutaneous with no evidence of extracutaneous manifestations after complete…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…, and most patients should be evaluated and usually managed at tertiary referral centers. Treatment First Steps Patients may be observed without therapy. Autoinvolution often occurs. Alternative Steps For a solitary lesion, excision may be curative….

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides: Overview

…of localized lesions (above). (c) Side effects include erythema, irritant dermatitis, urticaria, telangiectasia, and reversible bone marrow depression with pancytopenia. Later stage cutaneous T-cell lymphoma Patients in this category are best…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…d visceral or pulmonary. The above stages may be further classified using these subtypes: Subtype A: No signs or symptoms; Subtype B: Systemic symptoms (fever or weight loss). For stable cutaneous disease stages I and II, A or B:a. Intralesional…

Therapeutic Strategies in Dermatology

Alopecia: Key Points

…treatment for patients. Introduction Hair loss, or alopecia, is the result of increased shedding or breakage of hair and may be brought about by a broad spectrum of causes. Alopecia may result from primary disorders of hair or the hair follicle, and…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Clinical Cases

…cer that rapidly developed over the past four days without inciting trauma Currently using antibiotic ointment daily covered by a bandage Reports rapid progression of the ulcer Initial evaluation Thin, tired-appearing male Left leg ulcer that is…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Treatment

…esence of thromboses should prompt consideration of thrombotic disorders including cryoglobulinemia or anti-phospholipid antibody syndrome. Pitfalls Chilblain lupus erythematosus may present with lesions identical to idiopathic chilblain (pernio)….

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Key Points

…PV) is an autoimmune-mediated intraepidermal blistering disorder caused by the production of IgG autoantibodies to epidermal cellcell adhesion molecules (desmogleins 1 and 3, 160 and 130 kD respectively), resulting in separation and rounding up of…

Histologic Diagnosis of Inflammatory Skin Diseases

Adult T-cell leukemia/Lymphoma

…Lymphoma Presentation stereotypical Age and sex No predilection for sex. Middle-aged individuals from southern Japan and Caribbean Islands. Distribution of lesions Widespread Arrangement Scattered discrete lesions Individual lesions Papules,…