Search Results for: biopsy

Therapeutic Strategies in Dermatology

Lupus: Clinical Cases

…e workup for systemic lupus erythematosus (recent) Initial evaluation Diagnosis: Subacute cutaneous lupus (confirmed by skin biopsy) Fluocinonide 0.05% ointment b.i.d. Counseling on photoprotection and sun avoidance Vitamin D supplementation is…

Therapeutic Strategies in Dermatology

Warts: Treatment

…in between 10 and 30% of cases. Atypical, flat, and pigmented condylomata may suggest the diagnosis of bowenoid papulosis. A biopsy should be performed. This is often associated with HPV 16 or 18, and histologically may show features of squamous…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ried nature of cutaneous sarcoidal lesions and the easy accessibility of skin lesions and low morbidity associated with skin biopsy, dermatologists are often involved in helping make the diagnosis of sarcoidosis by skin biopsy to demonstrate the…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Initial Evaluation

…, or oral medicine specialist. Patients with skin lesions suspicious for PV should be referred to a dermatologist for a skin biopsy. The diagnosis of PV is made via biopsy of lesional skin or epithelium for H&E, and perilesional epithelium for…

Therapeutic Strategies in Dermatology

Dermatomyositis: Key Points

…ay to describe the cutaneous phenotypes that correlate with specific antibody profiles. If the diagnosis is in doubt, a skin biopsy may sometimes be helpful. Histopathologically, dermatomyositis is characterized by an interface dermatitis with…

Therapeutic Strategies in Dermatology

Venous Stasis: Treatment

…insufficiency as the etiology of the leg ulcer. In all ulcerations, if appropriate and progressive healing does not occur, a biopsy is indicated. Patients with a tendency to low leg ulcerations may have inherited or acquired defects in their…

Therapeutic Strategies in Dermatology

Eosinophilic Fasciitis: Overview

…py over 6-18 months. Most patients can be completely weaned off steroids. The initial work-up consists of an incisional skin biopsy that extends to include the fascia; total eosinophil count; and determinations of the ESR. Hypergammaglobulinemia may…

Therapeutic Strategies in Dermatology

Melanoma: Clinical Cases

…idly developed on the right leg A full-body skin examination is performed and does not identify any other suspicious lesions Biopsy: melanoma, 0.7 mm thickness, Clark’s level II. No ulceration present, and mitotic index <1 per mm2 She is...

Therapeutic Strategies in Dermatology

Lupus: Key Points

…ous-only lupus may meet criteria for systemic lupus erythematosus. The diagnosis of cutaneous lupus may be confirmed by skin biopsy, which in general reveals a vacuolar interface dermatitis, often in association with a lymphocytic infiltrate with…