Therapeutic Strategies in Dermatology

Warts: Treatment

…. Curettage of refractory acral lesions with or without shave biopsy of a portion for histopathologic evaluation may be useful. Local anesthesia (1% lidocaine) is required. Bleeding may be controlled with 20% aluminum chloride or very light electrode…

Therapeutic Strategies in Dermatology

Venous Stasis: Treatment

…ons, if appropriate and progressive healing does not occur, a biopsy is indicated. Patients with a tendency to low leg ulcerations may have inherited or acquired defects in their fibrinolytic systems. Appropriate evaluation for these conditions is in…

Therapeutic Strategies in Dermatology

Lupus: Key Points

…us. The diagnosis of cutaneous lupus may be confirmed by skin biopsy, which in general reveals a vacuolar interface dermatitis, often in association with a lymphocytic infiltrate with plasma cells, epidermal atrophy, and mucin. Variants exist, such a…

Therapeutic Strategies in Dermatology

Balanitis: Overview

…act dermatitis (e.g., from condoms or vaginal hygiene spray). Biopsy patients not responding to these measures. Circumcision will usually result in resolution in refractory cases. Pitfalls Do not make the diagnosis of a nonspecific balanitis until…

Therapeutic Strategies in Dermatology

Melanoma: Clinical Cases

…performed and does not identify any other suspicious lesions Biopsy: melanoma, 0.7 mm thickness, Clark’s level II. No ulceration present, and mitotic index <1 per mm2 She is diagnosed with Stage 1a melanoma Follow-up The patient goes for wide l…

Therapeutic Strategies in Dermatology

Eosinophilic Fasciitis: Overview

…steroids. The initial work-up consists of an incisional skin biopsy that extends to include the fascia; total eosinophil count; and determinations of the ESR. Hypergammaglobulinemia may also be found. Alternative Steps Hydroxyzine and cimetidine i…

Therapeutic Strategies in Dermatology

Alopecia: Treatment

…not clear or if not responding to treatment, consider a scalp biopsy. Androgenetic alopecia Topical minoxidil (2% solution or 5% solution or foam, such as generic minoxidil or Rogaine). Typically, 2% solution is used for females and 5% for males. Mi…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

…ong consideration should be given to performing an incisional biopsy for routine histology and cultures, and performing appropriate laboratory tests to exclude the above conditions. Pathergy occurs in many patients with PG, thus all but the most gent…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Clinical Cases

…bilateral axillae Diagnosis: hidradenitis suppurativa No skin biopsy is required Treatment options discussed; patient opts for systemic antibiotics. Rifampin 300 mg bid and clindamycin 300 mg b.i.d. is prescribed Intralesional triamcinolone 5 mg/cc i…