Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.9.1A: Perivascular and interstitial dermatitis + 10.9.1B: Lymphocytes, plasma cells, and eosinophils = Borreliosis In the United States, the findings pictured here are termed “erythema chronicum migrans” and are cons…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

“Dr Max Jessner: The lesions are flat, discoid, more or less elevated, pinkish to reddish brown, starting as small papular, expanding peripherally, sometimes clearing in the center, sometimes showing a circinate arrangement. The surface is sm…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

APOPTOSIS [Gk. apo- (away from) + ptosis (a falling)]: Reputed to be a specific type of cell death in which dead cells are said to undergo fragmentation by implosion with subsequent phagocytosis of nuclear debris (Fig. 3.40). The process is claimed…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

An algorithm is a method for calculation based on logical thought and orderly sequence, one that can be utilized for diagnosis of diseases of all kinds, including inflammatory ones of the skin. Once a disorder of the skin and/or subcutaneous fat has…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophoderma?

“Atrophoderma, or atrophia cutis. Atrophy of the skin may be quantitative or qualitative; idiopathic or symptomatic; diffused or circumscribed. Crocker gives this useful table: Pigmentosum Juvenilis Albidum Diffusum Senilis…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Figurate Erythemas?

“Erythema in Patches and Figured Erythema—These consist of congestive spots, patches, or surfaces of irregular shape, discoidal or of variable configuration (erythema marginatum or annulare, etc.). Although sometimes infectious, this t…

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema figuratum

Erythema figuratum Synonyms Erythema figuratum perstans Figurate erythema Annular erythema Presentation stereotypical Age and sex Adults of both sexes, but women especially Distribution of lesions Localized or widespread, trunk and proximal extremit…