Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…ecrobiosis lipoidica, necrobiotic xanthogranuloma, and severe burns of any cause, and as a consequence of the effects of neutrophils, in large number, on collagen, as occurs in “Churg-Strauss granulomas,” and on elastic fibers in elastosi…

Histologic Diagnosis of Inflammatory Skin Diseases

Delivery of Anesthesia

…should not be obtained by any method that utilizes freezing because the effect of extreme cold on the skin is equivalent to a burn, and the changes wrought, especially on the epidermis, are likely to impede any attempt at interpretation rationally….

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…c dermatitis The changes pictured are just like those of a sunburn. The position of the necrotic keratocytes, i.e., mostly in the upper part of the epidermis indicates that the injury to the skin came from outside it, rather than from within it. In c…

Histologic Diagnosis of Inflammatory Skin Diseases

Irritant contact dermatitis/Phototoxic dermatitis

…0 to 400 nm. Comment Irritant contact dermatitis is a type of burn and, that being so, the epidermis is marked by ballooned keratocytes that eventuate in vesiculation accompanied by reticular alteration, which, in turn, is affiliated invariably with…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema multiforme

…ets that peel off in the manner of lesions in a second-degree burn. It may be life threatening because of loss of fluids from skin unprotected by an epidermis. Lyell’s disease (toxic epidermal necrolysis) in adults is an expression fulminant of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Primary and Secondary Lesions?

…n erythematous patch, rubbing can elicit papules and plaques, burns of various kinds can result in vesicles and bullae; and nodules and tumors can be brought into being by injection of materials foreign to the skin. Furthermore, so-called secondary s…

Histologic Diagnosis of Inflammatory Skin Diseases

Pernio

…e in winter sports. The findings, i.e., purplish papules that burn, vesicles, and ulcerations on toes, fingers, ears, and nose, are more distinctive clinically than they are histopathologically, although both surely are diagnosable as lupus erythemat…