Histologic Diagnosis of Inflammatory Skin Diseases

Delivery of Anesthesia

When anesthesia is injected into a lesion about to be biopsied, it should be administered by syringe and not by Dermajet. The latter instrument forces fluid into the skin with such force that artifacts are produced that resemble the holes in Swiss c…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.53.1A: Perivascular dermatitis + 10.53.1B: Ballooned and individual necrotic keratocytes in the upper part of the epidermis = Phototoxic dermatitis In the realm of photodermatitis, the presence of many individual necrotic kerato…

Histologic Diagnosis of Inflammatory Skin Diseases

Pernio

Pernio Synonyms Dermatitis congelationis Chilblains Chilblain lupus Perniosis Erythema pernio Presentation stereotypical Age and sex Young persons usually with no predilection for either sex Distribution of lesions Fingers, toes, nose, and ears In…

Histologic Diagnosis of Inflammatory Skin Diseases

Irritant contact dermatitis/Phototoxic dermatitis

Irritant contact dermatitis/Phototoxic dermatitis Synonyms Acute nonallergic contact dermatitis Primary irritant dermatitis External toxidermas Irritant dermatitis Presentation stereotypical Age and sex Any age, both sexes Distribution of lesions Ex…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema multiforme

Erythema multiforme Synonyms Herpes iris Ectodermis erosive pluriorificialis Erytheme polymorphe Erythema multiforme exsudativum minor (Erythema multiforme minor, Erythema multiforme simplex, Erythema papulosum [Papular erythema multiforme]) Present…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Primary and Secondary Lesions?

“Some of the appearances observed in cutaneous diseases are caused directly by the deposition of morbid products in the skin. These bear the name of Primary symptoms or eruptions, Efflorescentiae cutaneae primariae. But these eruptions often…