Therapeutic Strategies in Dermatology

Behçet Syndrome: Overview

Overview BehÇet syndrome is a disorder of unknown cause characterized by oral and genital mucous membrane ulceration, erythema nodosum-like lesions, uveitis, and numerous other vascular, rheumatological, and gastrointestinal complications. Because t…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…ic vasculitis is present in skin lesions of some patients with Churg-Strauss syndrome, and Chu et al. speculated that leukocytoclastic vasculitis may be responsible for the formation of the granulomas named eponymically for Churg and Strauss. Their c…

Therapeutic Strategies in Dermatology

Appendigeal Tumors: Overview

Adnexal Tumors Both benign and malignant tumors may arise from the cutaneous adnexa (hair follicles, sweat glands, and sebaceous glands). Treatment First Steps A biopsy is usually necessary to establish the diagnosis, except for syringomas. Surgica…

Therapeutic Strategies in Dermatology

Cheilitis Granulomatosa: Overview

Melkersson-Rosenthal Syndrome Cheilitis granulomatosa is sudden onset of swelling of the lips which progresses to chronic enlargement. The Melkersson-Rosenthal syndrome diagnosis is made when lip enlargement is accompanied by facial paralysis or par…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Key Points

…nd trimesters of pregnancy), resulting in congenital varicella syndrome, a syndrome marked by significant morbidity and mortality to both mother and child. Herpes zoster Herpes zoster represents the reactivation of VZV from the cranial or dorsal root…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Treatment

Treatment Herpes zoster First-line therapy: The first-line therapy for herpes zoster includes the treatment of the acute eruption and therapy for herpetic neuralgia and post-herpetic neuralgia. Confirmation of herpes zoster by viral direct fluoresc…

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

Therapy First-line therapy: Prompt identification and discontinuation of the offending agent is an essential first step. In most cases, the cutaneous reaction will resolve in 2-5 days without therapy; patients may continue to get new lesions during…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Treatment

Treatment First-line therapy: The main treatment involves getting the affected areas warm, and keeping them warm. Wet, constrictive clothing should be removed immediately. The affected skin should be kept warm and dry, with loose, layered clothing,…

Therapeutic Strategies in Dermatology

Acne Vulgaris: Suggested Reading

Suggested Reading Bhate K, Williams HC (2013) Epidemiology of acne vulgaris, BJD, 168:474-485. Del Rosso JQ, Kim G (2009) Optimizing use of oral antibiotics in acne vulgaris; Dermatol Clin, 27(1):33-42. James WD (2005) Clinical practice. Acne; N Eng…