Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

…t that the lesion under discussion represented an intermediate step between nevus and melanoma. In an article by Clark and coworkers, they expressed this view in these words: “[dysplastic nevi] fit nicely into the schema of progression from hyp…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

…ocytic nevi are hamartomas, whereas acquired melanocytic nevi, such as those of Clark, Spitz, and Reed, are benign neoplasms), and they, of course, do not metastasize. Some melanomas begin in association with a preexisting nevus, especially superfici…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Normal, Typical, Ordinary, Banal, and Common Nevus?

…ysplastic (Clarks) nevus is more common by far than any so-called common nevus. Other melanocytic nevi, such as Unna’s, Miescher’s, and Spitz’s, also are common, but they are paltry in comparison to Clarks. In brief, t…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Therapeutic Strategies in Dermatology

Melanoma: Initial Evaluation

…red, purple). Nodular melanoma (NMM): Typically presents as a solitary nodule that arises from a pre-existing nevus or de novo. They may grow rapidly in thickness without radial spread (extension along the surface of the skin). Lentigo maligna melan…

Dermatology Practical & Conceptual

Melanoma arising in a giant nevus spilus maculosus

Abstract Melanoma arising in a nevus spilus is rare. There are two distinct types of nevus spilus characterized by macular or papular speckles, respectively. We report the case of a melanoma that arose in association with a giant nevus spilus maculo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus Cells, Nevocytes, and Nevomelanocytes?

“A nevus (mole) is a benign neoplasm of pigment-forming cells, the nevus cell.” Lookingbill DP, Marks JG Jr. Principles of clinical diagnosis. In: Moschella SL, Hurley HJ, eds. Dermatology. 3rd ed. Philadelphia, PA: WB Saunders Co., 19…

Dermatology Practical & Conceptual

Blue nevus with a starburst pattern on dermoscopy

…ent with a blue-gray papule approximately 4 mm in diameter. We suspected that it was a blue nevus or a pigmented Reed/Spitz nevus. On dermoscopic observation, the lesion showed homogeneous black-bluish pigmentation. This dermoscopic feature was sugge…