Search Results for: clark-like nevus

Therapeutic Strategies in Dermatology

Melanoma: Clinical Cases

…other suspicious lesions Biopsy: melanoma, 0.7 mm thickness, Clark’s level II. No ulceration present, and mitotic index <1 per mm2 She is diagnosed with Stage 1a melanoma Follow-up The patient goes for wide local excision with 1 cm margins; there…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blue Nevus?

…all of them are constituted of melanocytes. If a melanocytic nevus must consist of nests and fascicles of melanocytes, and at times of columns, cords, and strands of them, then “common” blue nevus, unlike “cellular” blue nevu…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus?

…d, nevus pertains to a birthmark, i.e., a hamartoma. The word nevus in dermatology, however, is not used simply as a synonym for birthmark. It also is applied to a particular acquired proliferation of melanocytes known as a melanocytic nevus, e.g., C…

Dermatology Practical & Conceptual

Melanoma arising in a giant nevus spilus maculosus

…of multiple dark-brown macules on a light brown, cafÉ-au-lait-like background (Figure 4). A punch biopsy of the nevus showed elongation of rete ridges and hyperpigmentation of basal keratinocytes but no substantial proliferation of melanocytes (Figur…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

…ly, clinically and molecularly, that the so-called dysplastic nevus is a type of melanocytic nevus and should be managed like other types of melanocytic nevi [1,2]. This reinforces the notion set forth by the late Bernie Ackerman, who asserted more t…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

…martomas, whereas acquired melanocytic nevi, such as those of Clark, Spitz, and Reed, are benign neoplasms), and they, of course, do not metastasize. Some melanomas begin in association with a preexisting nevus, especially superficial and “deep…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus Cells, Nevocytes, and Nevomelanocytes?

“A nevus (mole) is a benign neoplasm of pigment-forming cells, the nevus cell.” Lookingbill DP, Marks JG Jr. Principles of clinical diagnosis. In: Moschella SL, Hurley HJ, eds. Dermatology. 3rd ed. Philadelphia, PA: WB Saunders Co., 199…

Dermatology Practical & Conceptual

Blue nevus with a starburst pattern on dermoscopy

…e middle or upper reticular dermis [2]. On dermoscopy, a blue nevus is characterized by a homogeneous, structureless pigmentation, which is often described as steel-blue coloration [3]. Blue globules and dots, and pigment network-like structures are…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Normal, Typical, Ordinary, Banal, and Common Nevus?

…that is fairly closely bound. Most of the cells are exactly alike and very few, if any, nevus cells are observed to divide. Mole cells are commonly found close to the surface of the skin, sometimes nesting in parts of the epidermis.” http://ww…