Search Results for: clear-cell variant of squamous-cell carcinoma

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

…alogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of clinico-pathologic correlation, five distinctive types of basal…

Therapeutic Strategies in Dermatology

Warts: Treatment

…. A biopsy should be performed. This is often associated with HPV 16 or 18, and histologically may show features of squamous cell carcinoma in situ. Total eradication of these lesions should be attempted. They are treated in the same manner as…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…s universally by 3 months. Severe combined immunodeficiency syndrome and graft vs. host disease may closely mimic Langerhans cell histiocytosis. In Langerhans cell histiocytosis, most patients are immunologically normal prior to therapy when…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

…mary Paget’s is almost always associated with an underlying carcinoma. The data on extramammary Paget’s are less clear, but between 25% and 50% have an associated carcinoma. A careful lymph node evaluation is essential. Immunoperoxidase…

Therapeutic Strategies in Dermatology

Venous Stasis: Treatment

…o healing ones. They are also very effective in pain control. Pitfalls A non-healing ulcer may be cutaneous carcinoma (basal cell, squamous cell, etc.) or an inflammatory ulcer (such as pyoderma gangrenosum). Biopsy non-healing ulcerations after…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

…natomic site. Included among them are anaplastic large-cell lymphoma and panniculitis-like T-cell lymphoma. Anaplastic large-cell lymphoma of T-cell type usually occurs as a solitary, rapidly growing tumor. Most of the neoplastic lymphocytes express…

Therapeutic Strategies in Dermatology

Lichen Planus: Key Points

…planus, especially of the oral mucosa, genitalia, and rarely of the skin, may be complicated by the development of squamous cell carcinoma. Lichen planus may be triggered by or found in association with exogenous factors, such as medications or…

Therapeutic Strategies in Dermatology

Lichen Planus: Treatment

…ent, continue as required. Patients with ulcerative disease must be followed for the development of oral or genital squamous cell carcinoma. Optimal oral hygiene is an important adjunctive intervention in the management of oral lichen planus….