Search Results for: cleft

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…+ 10.23.11B: Focus of epidermal necrosis above a subepidermal cleft = Changes secondary to scratching Sharp fingernails applied with fury to the skin produce the findings shown here, namely, clefts between necrotic epidermis and dermis. The alteratio…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…al necrosis of the epidermis in conjunction with a suprabasal cleft. Below the cleft, some of the blood vessels were said to exhibit necrosis of the wall and occlusion of the lumen. Wise and Rein stated that lichen ruber moniliformis was unrelated to…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…1B: Lymphocytes, many necrotic keratocytes and a subepidermal cleft = Lichen planus-like keratosis, early  Because lichen planus-like keratosis often is misinterpreted clinically as basal-cell carcinoma, it sometimes, albeit uncommonly, is removed by…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…uoles become confluent, and, as a consequence, a subepidermal cleft comes into being. A cleft is an artifact, a space. When, however, serum finds its way into such a subepidermal space, a subepidermal blister results, and that happens episodically ab…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ular dermatitis, interface, vacuolar + 10.42.3B: Subepidermal cleft, ballooned keratocytes, necrotic keratocytes, and basket-weave orthokeratosis above parakeratosis = Graft-versus-host disease All of the findings illustrated are typical of an expres…

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…, intraepidermal neutrophilic pustules forming a suprabasilar cleft, and numerous multinucleated keratinocyte giant cells demonstrating nuclear molding were noted. There was a perivascular infiltrate in the upper dermis consisting of neutrophils and…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…both aligned parallel to the skin surface, and a subepidermal cleft = Scar, fully developed  A subepidermal cleft above a scar, unlike a blister that sometimes comes into being there, houses no serum. 10.96.6A: Fibrosing dermatitis + 10.96.6B: Plump…

Histologic Diagnosis of Inflammatory Skin Diseases

Darier’s disease and simulators of it

…mphocytes around venules of the superficial plexus Suprabasal clefts in discrete foci in the epidermis Above each cleft, acantholytic, dyskeratotic cells in the spinous and granular zones; some parakeratotic cells also acantholytic Epidermis, includi…

Dermatology Practical & Conceptual

Dermatoscopy of folliculosebaceous cystic hamartoma

…us connective tissue with thick collagen bundles (Figure 3A). Cleft formation between fibroepithelial units and intervening stroma was evident (Figure 3C). Moreover, the surrounding stroma was fibrotic, with a high number of small vessels (Figure 3C)…