Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

Overview The diagnosis of Paget’s disease or extramammary Paget’s is made when Paget cells are identified in histopathologic specimens from involved skin. The term Paget’s disease is used when the cutaneous lesion is identified inv…

Therapeutic Strategies in Dermatology

Erythema Annulare Centrifugum: Overview

…rings and dyes may all be triggers. The treatment is otherwise supportive. Gyrate erythemas are divided into superficial and deep types, the superficial types having the classic annular morphology and the “trailing” scale. The deep type a…

Therapeutic Strategies in Dermatology

Impetigo: Key Points

Key Points Impetigo is a highly contagious superficial cutaneous infection by Staphylococcus aureus and/or Streptococcus pyogenes. Effective treatment is directed at both organisms. Secondary impetigo, or impetiginization, may complicate preexistin…

Therapeutic Strategies in Dermatology

Folliculitis (including pseudofolliculitis barbae): Key Points

…aureus. Gram-negative forms occur, usually on the face, in the setting of chronic, broad-spectrum antibiotic therapy of acne vulgaris. Since inflammation is limited to the hair follicle, classic signs of infection (dolor, calor, rubor, and tumor) may…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…d. Alitretinoin gel 0.1% may be applied to macular lesions. e. Subsequently, for patients with stage II-A disease and helper T-cell counts over 200/mm3, intramuscular or subcutaneous A2 interferon 30 x 106 IU/m2 three times a week results in tumor re…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

…on and optimizing wound care. Inflammatory control may require systemic immunosuppression and/or the use of multiple therapeutic agents in combination. First steps Systemic corticosteroids are the initial treatment of choice for patients with establ…

Dermatology Practical & Conceptual

Pigmented tumor in the nostril

Abstract A 64-year-old man was noted to have a single pigmented lesion in the nostril of his nose. Clinical examination revealed a 5 mm nodular growth and brown lesion. With a presumed clinical diagnosis of malignant skin tumor, a biopsy was perform…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

…melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly shades of brown. A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nod…