Search Results for: darier\'s sign

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

Therapy First-line therapy: Prompt identification and discontinuation of the offending agent is an essential first step. In most cases, the cutaneous reaction will resolve in 2-5 days without therapy; patients may continue to get new lesions during…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Key Points

Key Points Pyoderma gangrenosum is a type of ulcerating neutrophilic dermatosis. The classic morphology of pyoderma gangrenosum is an ulcer with a violaceous rim and undermined border. PG lesions may develop very rapidly (in days) and may be…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ase, which is protean in its presentations but most commonly presents as papules, plaques, lupus pernio, or scar- or tattoo-associated lesions. Introduction Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating…

Therapeutic Strategies in Dermatology

Keratosis Pilaris: Treatment

…kin lesions and interventions to reduce inflammation are outlined below. Initial therapy A mild soap (e.g., Dove) or a soapless cleanser (e.g., Cetaphil, Cerave) should be used with a mild exfoliating scrub pad or washcloth. This treatment will…

A Clinical Atlas of 101 Common Skin Diseases

Porokeratosis

A constellation of conditions that assumes various forms clinically but whose most dependable denominator in common (the exception being the punctate manifestation) is a keratotic ring around a central zone of atrophy, e.g., in a congenital…

Therapeutic Strategies in Dermatology

Grover’s Disease / Transient Acantholytic Dermatosis: Treatment

Treatment First-line therapy: The first-line therapy for Grover’s is to suppress pruritus and when possible, reduce inflammation and clear lesions. First steps If TAD is not pruritic, treatment may not be required. A high-potency or superpotent…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Key Points

…tly inherited genodermatosis caused by dysregulation of calcium hemostasis in the keratinocyte that leads to acantholysis (loss of cell-cell adhesion) in the epidermis. Clinically, it manifests with macerated, eroded plaques primarily in the…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Initial Evaluation

…nd nails. Any lesions with significant crusting (or other signs of infection such as surrounding/spreading erythema, tenderness, or purulent exudates) are swabbed for bacterial culture. A skin biopsy from lesional skin is performed and submitted for…