Histologic Diagnosis of Inflammatory Skin Diseases

Images

…thematosus, discoid ┬áChanges identical to these may be seen in dermatomyositis. Only in two conditions of the skin is a basement membrane thickened in the manner of the one shown here, namely, discoid lupus erythematosus and dermatomyositis. 10…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Differential Diagnosis in Dermatopathology

Discussions

…papules, distinctive lesions on the acra of some patients with dermatomyositis, and in poikilodermatous lesions of the disease. Clinically, discoid lupus erythematosus can be divided roughly into early, fully developed, and late stages, just as can d…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

Degos’ disease (malignant atrophic papulosis) Synonyms Degos’ syndrome Malignant atrophic papulosis Papulosis atrophicans maligna Koehlmeier-Degos syndrome Thromboangiitis cutaneointestinalis disseminata Fatal cutaneointestinal syndrome…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Chondrodermatitis Nodularis Helicis?

…NH has been reported, in an 8-year-old child who suffered from dermatomyositis. We report another child with juvenile CNH who was not afflicted with dermatomyositis or other systemic disorders. The clinical and histologic evaluations demonstrated CNH…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…/chronic discoid lupus erythematosus, but may be noted also in dermatomyositis. In the differentiation of classic discoid lupus erythematosus from dermatomyositis, a moderately dense and deep infiltrate of lymphocytes is a clue to discoid lupus eryth…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Endothelial Swelling?

“In PLEVA, the more severe form, one observes vascular changes consisting of a pronounced mononuclear infiltrate around capillaries, with the capillaries showing endothelial swelling and permeation of their walls by the infiltrate. This usua…

Histologic Diagnosis of Inflammatory Skin Diseases

Bibliography

Bibliography Bibliography for dermatomyositis el-Azhary RA, Pakzad SY. Amyopathic dermatomyositis: retrospective review of 37 cases. J Am Acad Dermatol 2002;46(4):560-65. Golitz LE. Collagen diseases. J Cutan Pathol 1985;12:358-65. Hepp. ├ťber Pseudo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus versus Systemic Lupus Erythematosus? II

…hematosus. Systemic lupus erythematosus may be contrasted with dermatomyositis, systemic sclerosis, and Sj?gren’s syndrome, but not with skin diseases like poikilodermatomyositis, morphea, or discoid lupus erythematosus. Just as dermatomyositis

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…