Search Results for: diffuse neuroendocrine system (anachronistic)

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Key Points

…nvironments. Cases which persist or occur in association with systemic symptoms may be an indication of a multisystem disease such as chilblain lupus erythematosus, a rare variant of systemic lupus Introduction Chilblains, also termed pernio, is a be…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…. 5.174 A&B. Figure 5.174 A&B. Nodular dermatitis and diffuse dermatitis. Nodular dermatitis is distinguished from perivascular dermatitis (see Fig. 5.16 A&B) by the density of the infiltrate of inflammatory cells. In the perivascular der…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Trichodiscoma Related to the Hair Disk and Merkel-Cell Neoplasm to Merkel Cells?

…n: A tumor thought to arise from the cutaneous Merkel cell, a neuroendocrine cell.” MacKie RM. Epidermal skin tumors. In: Champion EH, Burton JL, Ebling FJG, eds. Textbook of Dermatology. 5th ed. Oxford, England: Blackwell Scientific Publicatio…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…ocytes often in mitosis = Lymphomatoid papulosis + Nodular or diffuse infiltrate of abnormal lymphocytes; lymphocytes often in the epidermis, sometimes in collections there = Mycosis fungoides     Acantholytic Cells in the Midst of Neutroph…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ly, as shown in the second set of photomicrographs. 11.23.4A: Diffuse dermatosis + 11.23.4B: Predominance of mast cells = Urticaria pigmentosa  This particular expression of urticaria pigmentosa is superficial, dense, and diffuse, in contrast to that…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Telogen Effluvium—An Inflammatory Disease?

…; Telogen effluvium is characterized clinically by temporary, diffuse, and sparse loss of hair that, as a rule, does not result in striking baldness. Only occasionally is the alopecia restricted clinically to a specific area (such as the occiput in n…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…keratotic, or both together Nodules and tumors Nodular and/or diffuse infiltrates of atypical lymphocytes throughout the dermis and sometimes in the subcutaneous fat Lymphocytes sometimes in lichenoid array; some dermal papillae stuffed by lymphocyte…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ompany with cholesterol clefts, and hairs situated in a dense diffuse infiltrate of histiocytes mostly = Foreign body reaction to ruptured infundibular cyst Sebaceous secretion is transported normally along sebaceous ducts to infundibula. It is not s…