Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…s shown in the second set of photomicrographs. 11.23.4A: Diffuse dermatosis + 11.23.4B: Predominance of mast cells = Urticaria pigmentosa ┬áThis particular expression of urticaria pigmentosa is superficial, dense, and diffuse, in contrast to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Telogen Effluvium—An Inflammatory Disease?

“Telogen effluvium signifies the loss of normal club hairs from resting follicles which have performed the ritual of involution, catagen, in the prescribed [sic] fashion. Inflammatory signs or other histologic abnormalities are necessarily m…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.38.1A: Pustular dermatitis, infundibular + 10.38.1B: A hair containing hyphae in an abscess = Suppurative infundibulitis of dermatophytic cause (Majocchi’s granuloma) The hair was spewed into the dermis when an infundibul…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

Mycosis fungoides Synonyms Cutaneous T-cell lymphoma Presentation stereotypical Age and Sex Adults usually, although children may be affected. Males preponderant. Distribution of lesions Often widespread, but sometimes localized to a single patch or…

Dermatology Practical & Conceptual

Study By Disease

…ustular (Quiz #178) Desmoplastic trichoepithelioma (Quiz #296) Diffuse large B-cell lymphoma (Quiz #387) Diffuse large B-cell lymphoma (Quiz #388) Diffuse large B-cell lymphoma (Quiz #611) Diffuse large B-cell lymphoma (Quiz #613) Disseminated superf…

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthogranuloma

…lasma cells around venules Late Fibroplasia amidst the dense diffuse infiltrate of foam cells Patchy mixed-cell infiltrate of lymphocytes, plasma cells, and eosinophils Correlation clinicopathologic Papules and nodules are expressions of dense dif…