Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Distinctive but Nonspecific Findings Using High Magnification

…), “porokeratosis” in any of its forms, and Bowen’s disease. ELASTOPHAGOCYTOSIS Engulfment of elastic or elastotic fibers by macrophages, a phenomenon that may be observed in any granulomatous process that develops in the reticular dermis, particula…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…Plump oval histiocytes make up the dermal infiltrate 5. No elastophagocytosis 5. Elastic fibers sometimes present in the cytoplasm of histiocytes 6. Papillary dermis sometimes involved 6. Papillary dermis spared 7. Fibrosis in longstanding les…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…idermolysis bullosa Epidermolytic Hyperkeratosis, e.g., Elastophagocytosis, e.g., Bullous congenital ichthyosiform erythroderma Granuloma annulare Ichthyosis hystrix Granulomatous slack skin (mycosis fungoides) A type of kerat…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

…cytes have engulfed elastotic material, a phenomenon known as elastophagocytosis and one not specific to granuloma annulare; it may be observed in any granulomatous process that takes place in a dermis replete with solar elastosis. The elastotic mate…