Therapeutic Strategies in Dermatology

Drug Eruptions: Clinical Cases

Clinical Cases Case 1 16-year-old girl with history of cutaneous wound infection Presents with morbilliform eruption 6 days after starting cephalosporin antibiotic No systemic symptoms Reports pruritus Initial evaluation Patient is well-appear…

A Clinical Atlas of 101 Common Skin Diseases

Hemangiomas, Vascular Malformations, and Ectasias

An hemangioma is a benign neoplasm of blood vessels, a vascular malformation is an aberration in development of one or more major vascular structures, and an ectasia is a dilation of a preexisting end vessel….

A Clinical Atlas of 101 Common Skin Diseases

Sclerodermas

A generic term for at least two different inflammatory diseases that have in common hardening of the skin by virtue of thickening of bundles of collagen in the dermis and subcutis. One of those diseases manifests itself as localized or widespread pa…

A Clinical Atlas of 101 Common Skin Diseases

Porphyria Cutanea Tarda

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes on…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

…es.” Wells GC. Recurrent granulomatous dermatitis with eosinophilia. Trans St John’s Hosp Dermatol Soc 1971;57:46–56. “Eosinophilic cellulitis (Wells’ syndrome) is an inflammatory dermatosis characterized by marked eo…

Histologic Diagnosis of Inflammatory Skin Diseases

Kimura’s disease

…ith countless eosinophils. Laboratory confirmation Peripheral eosinophilia is noted. Cause and mechanism Both are unknown. Comment Angiolymphoid hyperplasia with eosinophilia is reputed by some authors to be synonymous with Kimura’s disease. In…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Scleroderma?

…guttate form, lichen sclerosus et atrophicus, fasciitis with eosinophilia, and a manifestation of porphyria cutanea tarda) Linear (en coup de sabre and facial hemiatrophy) Both cutaneous and systemic Progressive systemic sclerosis Diffuse systemi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…ence of a clinical syndrome of severe asthma, fever, and hypereosinophilia, together with symptoms of vascular embarrassment in various organ systems, has been established. . . . The basic anatomical changes . . . consisted of widespread vascular les…

Differential Diagnosis in Dermatopathology

Discussions

…17;s disease” and “angiolymphoid hyperplasia with eosinophilia” as synonyms. In truth, these two diseases are different in nearly every respect and they are unrelated entirely to one another. Contrasting them in a work devoted to di…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…Ltd., 2001. Wells GC. Recurrent granulomatous dermatitis with eosinophilia. Trans St. John’s Hosp Dermatol Soc 1971;57:46-56. Ferreli C, Pinna AL, Atzori L, Aste N. Eosinophilic cellulitis (Wells’ syndrome): A new case description. J Eur…