Therapeutic Strategies in Dermatology

Drug Eruptions: Clinical Cases

Clinical Cases Case 1 16-year-old girl with history of cutaneous wound infection Presents with morbilliform eruption 6 days after starting cephalosporin antibiotic No systemic symptoms Reports pruritus Initial evaluation Patient is well-appear…

A Clinical Atlas of 101 Common Skin Diseases

Hemangiomas, Vascular Malformations, and Ectasias

An hemangioma is a benign neoplasm of blood vessels, a vascular malformation is an aberration in development of one or more major vascular structures, and an ectasia is a dilation of a preexisting end vessel….

A Clinical Atlas of 101 Common Skin Diseases

Sclerodermas

A generic term for at least two different inflammatory diseases that have in common hardening of the skin by virtue of thickening of bundles of collagen in the dermis and subcutis. One of those diseases manifests itself as localized or widespread pa…

A Clinical Atlas of 101 Common Skin Diseases

Porphyria Cutanea Tarda

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes on…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

…ry infiltration and subsequent granulomatous inflammation with eosinophilia, together with blood and bone marrow eosinophilia. Secondary Wells’ syndrome occurs with any eosinophilic reaction, such as insect bites with flame figures.” Bra…

Histologic Diagnosis of Inflammatory Skin Diseases

Kimura’s disease

…with countless eosinophils. Laboratory confirmation Peripheral eosinophilia is noted. Cause and mechanism Both are unknown. Comment Angiolymphoid hyperplasia with eosinophilia is reputed by some authors to be synonymous with Kimura’s disease. I…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Scleroderma?

…rophicus, en coup de sabre, facial hemiatrophy, fasciitis with eosinophilia, progressive systemic sclerosis, diffuse systemic sclerosis, CREST syndrome, and L-tryptophan-related eosinophilia-myalgia syndrome. Moreover, it is illogical to name a disea…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…of wheezing or diffuse high-pitched rales on expiration Eosinophilia Eosinophilia >10% on white blood cell differential count History of allergy* History of seasonal allergy (e.g., allergic rhinitis) or other documented allergies, inc…

Differential Diagnosis in Dermatopathology

Discussions

…spite these elements in common, angiolymphoid hyperplasia with eosinophilia and Kimura’s disease are distinguished easily from one another at scanning magnification. Angiolymphoid hyperplasia with eosinophilia is typified by very widely dilated…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

Arthropod assaults Synonyms Insect “bite” Bug bite Insect bite reaction Papular urticaria Lichen urticatus Strophulus Presentation stereotypical Age and sex Any age and both sexes Distribution of lesions At times only a single lesion a…