Search Results for: eosinophils

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…aricature of spongiosis, namely, spongiotic vesiculation, as is the case here. 10.10.7A: Vesicular dermatitis, subepidermal, eosinophils predominate + 10.10.7B: Many eosinophils in the dermis and in the subepidermal blister = Bullous pemphigoid,…

Histologic Diagnosis of Inflammatory Skin Diseases

Bullous pemphigoid

…in conjunction with spongiosis Fully developed (vesicular) Perivascular and interstitial infiltrate of lymphocytes and many eosinophils Numerous eosinophils throughout the edematous upper part of the dermis Subepidermal blister within which…

Histologic Diagnosis of Inflammatory Skin Diseases

Fixed drug eruption

…eratocytes in the spinous zone = Fixed drug eruption In this example of fixed drug eruption, neutrophils are few; in others, eosinophils are sparse. In sections of tissue from most specimens of fixed drug eruption, however, both neutrophils and…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

…ark-staining polymorphic nuclei and the “salt” by pale-staining cytoplasm. Figure 6.5 A&B. Identification of eosinophils at scanning and high magnifications. Eosinophils in this drug eruption are identifiable easily at scanning…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…neous fat. Pemphigus vulgaris, in its presentation as urticarial lesions, may be marked by spongiosis that is accompanied by eosinophils, but the number of eosinophils is relatively few compared with that in vesicles of incontinentia pigmenti, and…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…sebaceous glands Deposits of mucin in sebaceous lobules (epithelial mucinosis of “alopecia mucinosis”) at times Eosinophils may be numerous in the dermis, episodically the interstitium Eosinophils sometimes present in sebaceous lobules…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…asciitis, folliculitis, panniculitis, and spongiosis are not eosinophilic!; those -itides simply are accompanied by numerous eosinophils. Error: Eosinophils are a finding common in early lesions of mycosis fungoides. Reason: For practical purposes,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…it, only a few lymphocytes are found there. 10.111.5A: Perivascular and interstitial dermatitis + 10.111.5B: Lymphocytes and eosinophils around a venule and eosinophils and a few neutrophils in the interstitium = Urtica, early That this lesion still…