Search Results for: eosinophils

Histologic Diagnosis of Inflammatory Skin Diseases

Herpes gestationis

…in conjunction with spongiosis Fully developed (vesicular) Perivascular and interstitial infiltrate of lymphocytes and many eosinophils Numerous eosinophils throughout the edematous upper part of the dermis Subepidermal blister within which…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…aricature of spongiosis, namely, spongiotic vesiculation, as is the case here. 10.10.7A: Vesicular dermatitis, subepidermal, eosinophils predominate + 10.10.7B: Many eosinophils in the dermis and in the subepidermal blister = Bullous pemphigoid,…

Histologic Diagnosis of Inflammatory Skin Diseases

Bullous pemphigoid

…in conjunction with spongiosis Fully developed (vesicular) Perivascular and interstitial infiltrate of lymphocytes and many eosinophils Numerous eosinophils throughout the edematous upper part of the dermis Subepidermal blister within which…

Histologic Diagnosis of Inflammatory Skin Diseases

Fixed drug eruption

…eratocytes in the spinous zone = Fixed drug eruption In this example of fixed drug eruption, neutrophils are few; in others, eosinophils are sparse. In sections of tissue from most specimens of fixed drug eruption, however, both neutrophils and…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

…ark-staining polymorphic nuclei and the “salt” by pale-staining cytoplasm. Figure 6.5 A&B. Identification of eosinophils at scanning and high magnifications. Eosinophils in this drug eruption are identifiable easily at scanning…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…neous fat. Pemphigus vulgaris, in its presentation as urticarial lesions, may be marked by spongiosis that is accompanied by eosinophils, but the number of eosinophils is relatively few compared with that in vesicles of incontinentia pigmenti, and…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…it, only a few lymphocytes are found there. 10.111.5A: Perivascular and interstitial dermatitis + 10.111.5B: Lymphocytes and eosinophils around a venule and eosinophils and a few neutrophils in the interstitium = Urtica, early That this lesion still…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…eratocytes, some of them in clusters, favor lichen planus-like drug eruption rather than true lichen planus. The presence of eosinophils may be helpful in the identification of a drug eruption, but the finding of eosinophils is not requisite for…