Search Results for: epidermis

Histologic Diagnosis of Inflammatory Skin Diseases

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…sus, discoid, permanent alopecia Even at scanning magnification, it is possible to see that the interface between dermis and epidermis is smudged and the epidermis itself is thinned. In short, this alopecia is that of classic discoid lupus…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…ythematosus: The major finding distinguishing in a lesion developed fully is a thickened basement membrane beneath a thinned epidermis, at least in foci; the interface between epidermis and dermis has a smudged appearance. Lichenoid purpura of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mammary and Extramammary Paget’s Disease?

…;s disease. In extramammary Paget’s disease neoplastic cells of an apocrine carcinoma proliferate first within surface epidermis and, just like melanoma, descend infundibular epidermis and eccrine ducts. In contrast, in mammary Paget’s…

Histologic Diagnosis of Inflammatory Skin Diseases

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…formed collections (suppurative infundibulitis). Infundibula usually are spared in psoriasis, which tends to involve surface epidermis to the exclusion of infundibular epidermis. Sometimes, however, as shown here, an infundibulum may be caught up in…

Histologic Diagnosis of Inflammatory Skin Diseases

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…induced by scratching energetically. The cleft is artifactual, a consequence of poor adhesion of altered dermis to restored epidermis. The changes in the epidermis are a manifestation of persistent prolonged rubbing. 10.23.16A: Fibrosing dermatitis…