Dermatology Practical & Conceptual

Acantholytic dyskeratotic acanthoma: case report and review of the literature

…hs earlier as a non-healing, tender, raised area with central erosion. She had no personal or family history of keratosis follicularis (Darier’s disease), transient acantholytic dermatosis (Grover’s disease), non-melanoma skin cancer or melanoma. Cut…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Subcutaneous Fat: Panniculitis

…, is typical of a response to an assault by an arthropod. The erosion covered by crust represents the actual site of the “bite.” Figure 5.393 A&B. Granuloma annulare: dermal only. Granuloma annulare, typified by lymphocytes around…

Differential Diagnosis in Dermatopathology

Allergic (leukocytoclastic) vasculitis vs. Septic vasculitis

A small-vessel vasculitis characterized clinically by vesiculopustules on an erythematous base, purpuric macules and papules, and hemorrhagic bullae, and histopathologically by thrombi within venules, a consequence of sepsis….

Differential Diagnosis in Dermatopathology

Lymphomatoid papulosis vs. Mycosis fungoides, plaque

A small-vessel vasculitis characterized clinically by vesiculopustules on an erythematous base, purpuric macules and papules, and hemorrhagic bullae, and histopathologically by thrombi within venules, a consequence of sepsis….

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen simplex chronicus/Prurigo nodularis/Picker’s nodule/Erosions/Ulcers

…hen simplex chronicus/Prurigo nodularis/Picker’s nodule/Erosions/Ulcers Synonyms Lichen simplex chonicus (circumscribed neurodermatitis, lichen Vidal, lichen circumscripta, neurodermatitis, neurodermatitis circumscripta, lichen simplex, second…

Histologic Diagnosis of Inflammatory Skin Diseases

Atopic dermatitis

…r flexural surfaces, face, feet, and hands Individual lesions Erosions, ulcerations, crusts, lichenified papules, plaques, and nodules, and fissures in plaques at times; hemorrhagic crusts of excoriations often are disposed in linear array Course Les…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…collagen bundles in vertical streaks) and lively scratching (erosion and ulceration). 10.23.9A: Ulcer and crust, well circumscribed + 10.23.9B: Degeneration of bundles of collagen both in the upper part of the dermis and in a huge scale-cr…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphomatoid papulosis

…teration Spongiosis and even spongiotic vesiculation at times Erosion, ulceration, and scale-crust at times, the latter sometimes having neutrophils Monomorphous type, fully developed Wedge-shaped, superficial and deep, perivascular and interstitia…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…s and pustules, and necrosis) uncommon 9. Evidence of injury to the epidermis (spongiosis and ballooning, intraepidermal vesicles and pustules, and necrosis) nearly invariable 10. Erosion and ulceration uncommon 10. Erosion and ulceration common…