Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

Arthropod assaults Synonyms Insect “bite” Bug bite Insect bite reaction Papular urticaria Lichen urticatus Strophulus Presentation stereotypical Age and sex Any age and both sexes Distribution of lesions At times only a single lesion a…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphedema

Lymphedema Presentation stereotypical Age and sex Adults usually, women more than men Distribution of lesions Distal extremities, legs more than arms; genitalia episodically Arrangement of lesions Diffuse involvement of parts, e.g., elephantiasis In…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

An algorithm is a method for calculation based on logical thought and orderly sequence, one that can be utilized for diagnosis of diseases of all kinds, including inflammatory ones of the skin. Once a disorder of the skin and/or subcutaneous fat has…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…Eruptive capillary hemangioma (pyogenic granuloma) (Quiz #887) Erysipelas (Quiz #38) Erysipelas (Quiz #251) Erythema annular centrifugum (Quiz #505) Erythema annulare centrifugum (Quiz #56) Erythema annulare centrifugum (Quiz #212) Erythema annulare…

Histologic Diagnosis of Inflammatory Skin Diseases

Thrombophlebitis

Thrombophlebitis Presentation stereotypical Age and sex Women most commonly Distribution of lesions Localized to the lower extremities usually Arrangement of lesions Linear often, i.e., along the course of a vein Individual lesions Cord sometimes in…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

Neutrophils, eosinophils, lymphocytes, plasma cells, and histiocytes are called inflammatory cells because they enter tissue during the process of inflammation. A more exact designation for them is “cells of an inflammatory process”; the…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis chronica atrophicans

Acrodermatitis chronica atrophicans Presentation stereotypical Age and sex Middle aged to elderly women especially Distribution of lesions Distal part of extremities, particularly of legs; nodules develop especially near knees and elbows Configurati…