Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

“A case is presented exhibiting an unusual reaction of the skin to superficial trauma. In response to minor trauma, certain changes take place within the papillary layer of the corium characterized by affinity of the connective tissue for he…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

See Fig. 5.350 A&B. Figure 5.350 Fibrosing dermatitis. A. Early. B. Late (sclerosis). Fibrosing dermatitis (as well as fibrosing peri-infundibulitis/perifolliculitis and fibrosing panniculitis) results, in every instance, from injury to nonep…

Histologic Diagnosis of Inflammatory Skin Diseases

Atopic dermatitis

…part of the epidermis is a clue to injury external, such as by excoriation. Erosion or ulceration in a focus above a scant infiltrate of inflammatory cells in the upper part of the dermis is a clue to excoriation vigorously. Bundles of degenerated co…

Histologic Diagnosis of Inflammatory Skin Diseases

Reactive perforating collagenosis

Reactive perforating collagenosis Presentation stereotypical Age and sex Any age, both sexes Distribution of lesions Asymmetric at sites of trauma; sometimes symmetrical Arrangement of lesions May be linear Individual lesions Ulcerated papules toppe…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Site

…ruritic, scratching is an inevitable consequence, and signs of excoriation are nearly invariable. Excoriation produces erosions, ulcerations, and crusts, and, sometimes, is followed by evidences of impetiginization. Ulcers may heal with scar. Clinici…

Histologic Diagnosis of Inflammatory Skin Diseases

Macular and papular (lichenoid) amyloidosis-Cutaneous solely

…iar inflammatory disease on which is imposed signs dramatic of excoriation furious. Effects of excoriation alone are not affiliated with a net-like or rippled pattern; either is lichen simplex chronicus alone. Miscue clinical as clue to diagnosis his…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Primary and Secondary Lesions?

“Some of the appearances observed in cutaneous diseases are caused directly by the deposition of morbid products in the skin. These bear the name of Primary symptoms or eruptions, Efflorescentiae cutaneae primariae. But these eruptions often…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Study By Disease

…iosclerosis and atherosclerosis (Quiz #835) Ulcer secondary to excoriation (Quiz #167) Ulcer secondary to excoriation (Quiz #169) Ulcer secondary to maceration, in this instance by the effects of urine (Quiz #238) Ulcer secondary to the effects of ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.5.1A: Perivascular and interstitial dermatitis + 10.5.1B: Lymphocytes and eosinophils around venules, and neutrophils in the interstitium in conjunction with degeneration of bundles of collagen focally = Response to an arthropod…