Search Results for: fibrocytes

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

…parallel bundles arranged in striking storiform pattern.” Three of the lesions were hypocellular with scant, elongated fibrocytes positioned as solitary units among bundles of collagen, whereas the other lesion showed a proliferation of plump…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…nd in abundance. 10.54.3A: Fibrosing dermatitis + 10.54.3B: Markedly thickened bundles of collagen in random array and plump fibrocytes aligned along the long axis of those bundles = Keloid In time, fibrocytes in a keloid become thin and mucin in…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…bundles in the dermis. Dermal dendrocytes, a heterogeneous population, are indistinguishable by conventional microscopy from fibrocytes and, like fibrocytes, are scattered throughout the dermis. The exact nosologic status of these cells,…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…plays histiocytes (lipophages and siderophages in early lesions), in company with innumerable extravasated erythrocytes, and fibrocytes in conjunction with coarse bundles of collagen, both components being arranged randomly. At the periphery of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…cleft = Lichen sclerosus et atrophicus (superficial morphea) + Sclerosis throughout much or all of the dermis with abnormal fibrocytes in the upper part of it = Radiation sclerosis + Fibrin beneath a cleft and chondrocytoid fibrocytes in…

Histologic Diagnosis of Inflammatory Skin Diseases

Our Definition of “Inflammation” and “Inflammatory Disease”

…possible by conventional miscroscopy to determine whether particular cells, e.g., plasma cells, mast cells, histiocytes, and fibrocytes in a particular circumstance are inflammatory or neoplastic, e.g., “monster cells” in dermatofibroma…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…pressure; the hyperkeratosis, hypergranulosis, and epidermal hyperplasia are indications of prolonged rubbing. Chondrocytoid fibrocytes are expected in granulation tissue at the side of fibrin positioned subepithelially in a lesion on an ear….