Search Results for: fibrocytes

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…bundles in the dermis. Dermal dendrocytes, a heterogeneous population, are indistinguishable by conventional microscopy from fibrocytes and, like fibrocytes, are scattered throughout the dermis. The exact nosologic status of these cells,…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatofibroma

…well-circumscribed nodule in the reticular dermis and, at times, the upper part of the subcutaneous fat Collagen bundles and fibrocytes sometimes arrayed in short fascicles that interweave Fibrocytes interposed between thickened collagen bundles at…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…plays histiocytes (lipophages and siderophages in early lesions), in company with innumerable extravasated erythrocytes, and fibrocytes in conjunction with coarse bundles of collagen, both components being arranged randomly. At the periphery of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…y different from morphea and scleromyxedema. 10.69.2A: Fibrosing dermatitis, panniculitis, septal, and fasciitis + 10.69.2B: Fibrocytes scattered among wavy bundles of collagen = Nephrogenic fibrosing dermopathy At scanning magnification, the…

Histologic Diagnosis of Inflammatory Skin Diseases

Our Definition of “Inflammation” and “Inflammatory Disease”

…possible by conventional miscroscopy to determine whether particular cells, e.g., plasma cells, mast cells, histiocytes, and fibrocytes in a particular circumstance are inflammatory or neoplastic, e.g., “monster cells” in dermatofibroma…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…cleft = Lichen sclerosus et atrophicus (superficial morphea) + Sclerosis throughout much or all of the dermis with abnormal fibrocytes in the upper part of it = Radiation sclerosis + Fibrin beneath a cleft and chondrocytoid fibrocytes in…