Histologic Diagnosis of Inflammatory Skin Diseases

Nodular fasciitis

…Granulation tissue in and above the fascia Fully developed Fibroplasia accompanying granulation tissue Fibrocytes with large oval nuclei and, sometimes, an elongated tail of cytoplasm; some multinucleate Abundant mucin in the zone of fibrosing gra…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…cular dermatitis, interface, patchy lichenoid + 10.60.9B: Fibroplasia and melanophages in the papillary dermis, lymphocytes at the dermoepidermal junction, a thinned epidermis, hypergranulosis, and orthokeratosis = Lichen planus, atrophic ¬†Atroph…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

…e crown of the scalp; infiltration by lymphocytes followed by fibroplasia around the upper part of follicles; complete destruction eventually of follicles with replacement of them by “dense collagen”, and sparing of muscles of hair erecti…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ere are a consequence of the effects of scratching furiously. Fibroplasia limited to the upper part of the dermis is a telltale sign of superficial ulceration previous at this site. The scale-crust that houses many neutrophils is another consequence…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ronic ¬†The longstanding nature of the process is evidenced by fibroplasia throughout much of the dermis. In addition to dilated lymphatics, there are changes in blood vessels characteristic of severe stasis. 11.12.2A: Fibrosing dermatosis +…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

…to such usually seen in dermal melanocytic populations [41]. Fibroplasia may be impressive, in particular in dermal variants of Spitz nevi [22]. Dermatoscopically, Spitz nevi are typified by nuances of a globular pattern, frequently associated with…

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthogranuloma

…stiocytes; lymphocytes and plasma cells around venules Late Fibroplasia amidst the dense diffuse infiltrate of foam cells Patchy mixed-cell infiltrate of lymphocytes, plasma cells, and eosinophils Correlation clinicopathologic Papules and nodules…

Histologic Diagnosis of Inflammatory Skin Diseases

Keloid

…of years. Findings histopathologic Early Granulation tissue Fibroplasia that vaguely resembles a hypertrophic scar, i.e., an increased number of fibrocytes and fibrillary bundles of collagen seemingly in haphazard array Fully developed Numerous t…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

…ntly from external trauma, usually in the form of a puncture or a yank of a “hang nail.” In time, the proliferation of vessels ceases, there is progressive fibroplasia, and the then gray or white papule shrinks and eventually disappears….