Histologic Diagnosis of Inflammatory Skin Diseases

Nodular fasciitis

Nodular fasciitis Synonyms Proliferative fasciitis Subcutaneous pseudocarcinomatous fibromatosis Presentation stereotypical Age and sex Young adults of both sexes Distribution of lesions Localized to extremities, forearms mostly, in adults, but to…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.60.1A: Perivascular dermatitis, interface, focally lichenoid + 10.60.1B: Obscuration of the dermoepidermal junction by lymphocytes, jagged acanthosis, wedge-shaped hypergranulosis, and compact orthokeratosis = Lichen planus, ear…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

“An irreversible alopecia of the scalp occurs in negro women who straighten their hair with hot combs. The disease is common and distinctive, clinically and histopathologically. . . . Hot petrolatum used with the comb causes a chronic inflamm…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.23.1A: Perivascular dermatitis, psoriasiform + 10.23.1B: Orthokeratosis, hypergranulosis, acanthosis, proliferation of infundibular and eccrine ductal keratocytes, and coarse bundles of collagen in vertical streaks = Lichen simp…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.12.1A: Fibrosing dermatitis + 11.12.1B: Widely dilated lymphatics in company with an increased number of thick-walled blood vessels lined by plump endothelial cells, those vessels in the upper part of the dermis being oriented m…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

Objective Although conflicting with the concept of nevi being hamartomas, to date, Spitz and Reed nevi have been regarded as acquired melanocytic nevi, whereas many other types have already been accepted as being congenital. Here, the reader will fi…

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthogranuloma

Xanthogranuloma Synonyms Juvenile xanthogranuloma Nevoxanthoendothelioma Nevoxanthoma Juvenile xanthoma Juvenile giant cell granuloma Xanthoma multiplex Multiple eruptive xanthoma in infancy Congenital xanthoma tuberosum Xanthoma naeviforme Presen…

Differential Diagnosis in Dermatopathology

Discussions

…a Spitz’s nevus to become desmoplastic. Parenthetically, fibroplasia in a melanocytic nevus is not limited to Spitz’s nevus. It is seen in Clark’s nevi (“concentric”/”lamellar” fibroplasia), some long-lasting…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

A red, often ulcerated, boggy papule that represents a hyperplasia of small cutaneous vessels which are "fed" by an arteriole in the subcutaneous fat, the lesion resulting consistently from external trauma, usually in the form of a punctur…