Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease)

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Darier’s Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Raynaud’s Phenomenon/Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Mucha-Habermann Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Leprosy/Hansen’s Disease and Reactional States

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

Key Points Sarcoidosis is a multisystem inflammatory disease, characterized by non-caseating granulomas, which occurs in patients of all ages and ethnic groups. Patients require thorough evaluation for multisystem disease and close monitoring for t…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…tomatic, and only 20% of patients with classic KS die of their disease. For this reason, therapy is often palliative and directed at control of local symptoms. Progressive disease may require more aggressive therapy. First Steps For localized or lim…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…onally deficient. This disorder is classified as single-system disease, multisystem disease, or multisystem disease with organ dysfunction. The skin is one of the most frequently affected organs in patients with both localized (skin only) and multisy…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

…atment First-line therapy: The first-line therapy for Darier’s disease is systemic retinoids. First steps The currently accepted primary treatment of moderate-to-severe Darier’s disease is systemic retinoids. Isotretinoin and acitretin are equally e…