Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of clin…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

…in clusters on any anatomic site. When “primary,” B-cell lymphomas of the skin seem to be wholly cutaneous with no evidence of extracutaneous manifestations after complete staging has been performed. The major categories of primary cutaneou…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been arrest…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…Overview Kaposi’s sarcoma (KS) results from endothelial cell proliferation caused by infection with human herpesvirus 8 and occurs in four settings: classic KS, African (endemic) KS, immunosuppressive-associated KS, and AIDS-associated KS. The…

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides: Overview

Overview Therapy of cutaneous T-cell lymphoma often requires specialized knowledge, and for this reason it is often appropriate to refer such patients to a medical center with specialized knowledge in the management of CTCL. Since early aggressive t…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

…dermatitis, Hailey-Hailey or Darier’s disease, axillary granular parakeratosis, Kawasaki syndrome, as well as cutaneous malignancies such as squamous cell carcinoma, extramammary Paget’s disease, or histiocytosis. It is important to note…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

…in clusters on any anatomic site. When “primary,” B-cell lymphomas of the skin seem to be wholly cutaneous with no evidence of extracutaneous manifestations after complete staging has been performed. The major categories of primary cutaneou…

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

…in clusters on any anatomic site. When “primary,” B-cell lymphomas of the skin seem to be wholly cutaneous with no evidence of extracutaneous manifestations after complete staging has been performed. The major categories of primary cutaneou…

A Clinical Atlas of 101 Common Skin Diseases

Ichthyoses

Noninflammatory scaly disorders in which polygonal gray or brown scales tend to be elevated at their periphery, causing them to appear to be separated from contiguous scales, findings that are seen in three conditions, namely, ichthyosis vulgaris (a…