Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of clin…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa/ Mastocytosis: Overview

…GI complaints, and headaches can result from circulating mast cell products released when the mastocytoma is rubbed or irritated. These symptoms may require treatment. Treatment First steps Children with localized mast cell tumors are best treated b…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

Malignant neoplasms of B-lymphocytes especially that present themselves usually as papules, nodules, and tumors, sometimes solitary but at other times numerous, and often in clusters on any anatomic site. When "primary," B-cell lymphomas o…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been arrest…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

Overview Kaposi’s sarcoma (KS) results from endothelial cell proliferation caused by infection with human herpesvirus 8 and occurs in four settings: classic KS, African (endemic) KS, immunosuppressive-associated KS, and AIDS-associated KS. The…

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides: Overview

Overview Therapy of cutaneous T-cell lymphoma often requires specialized knowledge, and for this reason it is often appropriate to refer such patients to a medical center with specialized knowledge in the management of CTCL. Since early aggressive t…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

…dermatitis, Hailey-Hailey or Darier’s disease, axillary granular parakeratosis, Kawasaki syndrome, as well as cutaneous malignancies such as squamous cell carcinoma, extramammary Paget’s disease, or histiocytosis. It is important to note…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

Malignant neoplasms of B-lymphocytes especially that present themselves usually as papules, nodules, and tumors, sometimes solitary but at other times numerous, and often in clusters on any anatomic site. When "primary," B-cell lymphomas o…