Search Results for: granular-cell schwannoma

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…s universally by 3 months. Severe combined immunodeficiency syndrome and graft vs. host disease may closely mimic Langerhans cell histiocytosis. In Langerhans cell histiocytosis, most patients are immunologically normal prior to therapy when…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Key Points

…c pemphigus is made similarly to that for pemphigus vulgaris; however, on direct immunofluorescence, in addition to the intercellular deposition of IgG, there may be deposition of IgG along the dermoepidermal junction (linear or granular pattern)…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

…sis rosea, allergic or irritant contact dermatitis, deficiency dermatitis, Hailey-Hailey or Darier’s disease, axillary granular parakeratosis, Kawasaki syndrome, as well as cutaneous malignancies such as squamous cell carcinoma, extramammary…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

A Clinical Atlas of 101 Common Skin Diseases

Ichthyoses

Noninflammatory scaly disorders in which polygonal gray or brown scales tend to be elevated at their periphery, causing them to appear to be separated from contiguous scales, findings that are seen in three conditions, namely, ichthyosis vulgaris…

Therapeutic Strategies in Dermatology

Pruritic Urticarial Papules and Plaques of Pregnancy: Initial Evaluation

…a skin biopsy and direct immunofluorescence (DIF) should be obtained. DIF in PUPPP is typically negative but rarely can have granular C3, IgM or IgA at the dermoepidermal junction. In contrast, pemphigoid gestationis is characterized by linear C3 at…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…phagocytic, which includes circulating monocytes and tissue macrophages, and (2) dendritic, which includes Langerhans’ cells, dendritic cells, and interdigitating reticulum cells of lymph nodes. Langerhans’ cells differ from macrophages…