Search Results for: granular-cell schwannoma

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…s universally by 3 months. Severe combined immunodeficiency syndrome and graft vs. host disease may closely mimic Langerhans cell histiocytosis. In Langerhans cell histiocytosis, most patients are immunologically normal prior to therapy when…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Key Points

…c pemphigus is made similarly to that for pemphigus vulgaris; however, on direct immunofluorescence, in addition to the intercellular deposition of IgG, there may be deposition of IgG along the dermoepidermal junction (linear or granular pattern)…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

…sis rosea, allergic or irritant contact dermatitis, deficiency dermatitis, Hailey-Hailey or Darier’s disease, axillary granular parakeratosis, Kawasaki syndrome, as well as cutaneous malignancies such as squamous cell carcinoma, extramammary…

Therapeutic Strategies in Dermatology

Linear IgA Bullous Dermatosis: Initial Evaluation

…). Sometimes IgG deposits are also seen in both adults and children. Differential Diagnosis Dermatitis herpetiformis On DIF, granular deposition of IgA at BMZ Less likely to see intact vesicles given highly pruritic Very high association with gluten…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Therapeutic Strategies in Dermatology

Pruritic Urticarial Papules and Plaques of Pregnancy: Initial Evaluation

…a skin biopsy and direct immunofluorescence (DIF) should be obtained. DIF in PUPPP is typically negative but rarely can have granular C3, IgM or IgA at the dermoepidermal junction. In contrast, pemphigoid gestationis is characterized by linear C3 at…

Balloon cell melanoma in primary care practice: a case report

Balloon cell melanoma in primary care practice: a case report

…s [3]. The foamy cells are usually sparser in primary melanomas than subsequent metastases [3]. In contrast to balloon nevus cells, the cells of BCMM generally lack melanin [16]. Sparse quantities of melanin granules were only found in 9 cases of…